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Discovery of novel allosteric mitogen-activated protein kinase kinase (MEK) 1,2 inhibitors possessing bidentate Ser212 interactions.
Heald RA, Jackson P, Savy P, Jones M, Gancia E, Burton B, Newman R, Boggs J, Chan E, Chan J, Choo E, Merchant M, Rudewicz P, Ultsch M, Wiesmann C, Yue Q, Belvin M, Price S. Heald RA, et al. Among authors: jones m. J Med Chem. 2012 May 24;55(10):4594-604. doi: 10.1021/jm2017094. Epub 2012 May 3. J Med Chem. 2012. PMID: 22506516
Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform.
Staben ST, Ndubaku C, Blaquiere N, Belvin M, Bull RJ, Dudley D, Edgar K, Gray D, Heald R, Heffron TP, Jones GE, Jones M, Kolesnikov A, Lee L, Lesnick J, Lewis C, Murray J, McLean NJ, Nonomiya J, Olivero AG, Ord R, Pang J, Price S, Prior WW, Rouge L, Salphati L, Sampath D, Wallin J, Wang L, Wei B, Weismann C, Wu P. Staben ST, et al. Among authors: jones m, jones ge. Bioorg Med Chem Lett. 2013 May 1;23(9):2606-13. doi: 10.1016/j.bmcl.2013.02.102. Epub 2013 Mar 7. Bioorg Med Chem Lett. 2013. PMID: 23540645
Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy.
Chin WL, Cook AM, Chee J, Principe N, Hoang TS, Kidman J, Hmon KPW, Yeow Y, Jones ME, Hou R, Denisenko E, McDonnell AM, Hon CC, Moody J, Anderson D, Yip S, Cummins MM, Stockler MR, Kok PS, Brown C, John T, Kao SC, Karikios DJ, O'Byrne KJ, Hughes BGM, Lake RA, Forrest ARR, Nowak AK, Lassmann T, Lesterhuis WJ. Chin WL, et al. Among authors: jones me. Cell Rep Med. 2024 Dec 18:101882. doi: 10.1016/j.xcrm.2024.101882. Online ahead of print. Cell Rep Med. 2024. PMID: 39731918 Free article.
Recurring incursions and dissemination of novel Eurasian-origin H5Nx avian influenza viruses in Atlantic Canada.
Rahman I, Erdelyan CNG, Signore AV, Ayilara I, Wight J, Jones MEB, Sullivan DS, Lung O, Hisanaga T, Wilhelm SI, Cunningham JT, Ward CRE, Bosch J, Robertson GJ, Gosse K, Baker M, Dawe B, Lair S, Provencher JF, Hargan KE, Berhane Y, Lang AS. Rahman I, et al. Among authors: jones meb. Virus Evol. 2024 Dec 17;10(1):veae111. doi: 10.1093/ve/veae111. eCollection 2024. Virus Evol. 2024. PMID: 39722685 Free PMC article.
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