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Page 1
Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis.
Hoshi H, Hao W, Fujita Y, Funayama A, Miyauchi Y, Hashimoto K, Miyamoto K, Iwasaki R, Sato Y, Kobayashi T, Miyamoto H, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Kitagawa K, Nakayama KI, Kawamoto T, Sano M, Fukuda K, Ohsawa I, Ohta S, Morioka H, Matsumoto M, Chiba K, Toyama Y, Miyamoto T. Hoshi H, et al. Among authors: morioka h. J Bone Miner Res. 2012 Sep;27(9):2015-23. doi: 10.1002/jbmr.1634. J Bone Miner Res. 2012. PMID: 22508505 Free article.
Osteoclast stimulatory transmembrane protein and dendritic cell–specific transmembrane protein cooperatively modulate cell–cell fusion to form osteoclasts and foreign body giant cells.
Miyamoto H, Suzuki T, Miyauchi Y, Iwasaki R, Kobayashi T, Sato Y, Miyamoto K, Hoshi H, Hashimoto K, Yoshida S, Hao W, Mori T, Kanagawa H, Katsuyama E, Fujie A, Morioka H, Matsumoto M, Chiba K, Takeya M, Toyama Y, Miyamoto T. Miyamoto H, et al. Among authors: morioka h. J Bone Miner Res. 2012 Jun;27(6):1289-97. doi: 10.1002/jbmr.1575. J Bone Miner Res. 2012. PMID: 22337159 Free article.
PDGFBB promotes PDGFRα-positive cell migration into artificial bone in vivo.
Yoshida S, Iwasaki R, Kawana H, Miyauchi Y, Hoshi H, Miyamoto H, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Kobayashi T, Sato Y, Miyamoto K, Morioka H, Matsumoto M, Chiba K, Toyama Y, Nakagawa T, Miyamoto T. Yoshida S, et al. Among authors: morioka h. Biochem Biophys Res Commun. 2012 May 18;421(4):785-9. doi: 10.1016/j.bbrc.2012.04.084. Epub 2012 Apr 23. Biochem Biophys Res Commun. 2012. PMID: 22554514
Bcl6 promotes osteoblastogenesis through Stat1 inhibition.
Fujie A, Funayama A, Miyauchi Y, Sato Y, Kobayashi T, Kanagawa H, Katsuyama E, Hao W, Tando T, Watanabe R, Morita M, Miyamoto K, Kanaji A, Morioka H, Matsumoto M, Toyama Y, Miyamoto T. Fujie A, et al. Among authors: morioka h. Biochem Biophys Res Commun. 2015 Feb 13;457(3):451-6. doi: 10.1016/j.bbrc.2015.01.012. Epub 2015 Jan 15. Biochem Biophys Res Commun. 2015. PMID: 25597995
Methotrexate inhibits osteoclastogenesis by decreasing RANKL-induced calcium influx into osteoclast progenitors.
Kanagawa H, Masuyama R, Morita M, Sato Y, Niki Y, Kobayashi T, Katsuyama E, Fujie A, Hao W, Tando T, Watanabe R, Miyamoto K, Morioka H, Matsumoto M, Toyama Y, Saya H, Miyamoto T. Kanagawa H, et al. Among authors: morioka h. J Bone Miner Metab. 2016 Sep;34(5):526-31. doi: 10.1007/s00774-015-0702-2. Epub 2015 Jul 23. J Bone Miner Metab. 2016. PMID: 26202855
MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner.
Miyamoto K, Ninomiya K, Sonoda KH, Miyauchi Y, Hoshi H, Iwasaki R, Miyamoto H, Yoshida S, Sato Y, Morioka H, Chiba K, Egashira K, Suda T, Toyama Y, Miyamoto T. Miyamoto K, et al. Among authors: morioka h. Biochem Biophys Res Commun. 2009 Jun 5;383(3):373-7. doi: 10.1016/j.bbrc.2009.04.020. Epub 2009 Apr 11. Biochem Biophys Res Commun. 2009. PMID: 19364494
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.
Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T. Miyauchi Y, et al. Among authors: morioka h. J Exp Med. 2010 Apr 12;207(4):751-62. doi: 10.1084/jem.20091957. Epub 2010 Apr 5. J Exp Med. 2010. PMID: 20368579 Free PMC article.
Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization.
Miyamoto K, Yoshida S, Kawasumi M, Hashimoto K, Kimura T, Sato Y, Kobayashi T, Miyauchi Y, Hoshi H, Iwasaki R, Miyamoto H, Hao W, Morioka H, Chiba K, Kobayashi T, Yasuda H, Penninger JM, Toyama Y, Suda T, Miyamoto T. Miyamoto K, et al. Among authors: morioka h. J Exp Med. 2011 Oct 24;208(11):2175-81. doi: 10.1084/jem.20101890. Epub 2011 Oct 17. J Exp Med. 2011. PMID: 22006978 Free PMC article.
Conditional inactivation of Blimp1 in adult mice promotes increased bone mass.
Miyauchi Y, Miyamoto H, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Hoshi H, Miyamoto K, Sato Y, Kobayashi T, Akiyama H, Morioka H, Matsumoto M, Toyama Y, Miyamoto T. Miyauchi Y, et al. Among authors: morioka h. J Biol Chem. 2012 Aug 17;287(34):28508-17. doi: 10.1074/jbc.M112.356634. Epub 2012 Jul 3. J Biol Chem. 2012. PMID: 22761448 Free PMC article.
An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion.
Miyamoto H, Katsuyama E, Miyauchi Y, Hoshi H, Miyamoto K, Sato Y, Kobayashi T, Iwasaki R, Yoshida S, Mori T, Kanagawa H, Fujie A, Hao W, Morioka H, Matsumoto M, Toyama Y, Miyamoto T. Miyamoto H, et al. Among authors: morioka h. J Biol Chem. 2012 Sep 21;287(39):32479-84. doi: 10.1074/jbc.M112.358226. Epub 2012 Aug 3. J Biol Chem. 2012. PMID: 22865856 Free PMC article.
605 results