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A nonazole CYP51 inhibitor cures Chagas' disease in a mouse model of acute infection.
Doyle PS, Chen CK, Johnston JB, Hopkins SD, Leung SS, Jacobson MP, Engel JC, McKerrow JH, Podust LM. Doyle PS, et al. Among authors: jacobson mp. Antimicrob Agents Chemother. 2010 Jun;54(6):2480-8. doi: 10.1128/AAC.00281-10. Epub 2010 Apr 12. Antimicrob Agents Chemother. 2010. PMID: 20385875 Free PMC article.
A cysteine protease inhibitor rescues mice from a lethal Cryptosporidium parvum infection.
Ndao M, Nath-Chowdhury M, Sajid M, Marcus V, Mashiyama ST, Sakanari J, Chow E, Mackey Z, Land KM, Jacobson MP, Kalyanaraman C, McKerrow JH, Arrowood MJ, Caffrey CR. Ndao M, et al. Among authors: jacobson mp. Antimicrob Agents Chemother. 2013 Dec;57(12):6063-73. doi: 10.1128/AAC.00734-13. Epub 2013 Sep 23. Antimicrob Agents Chemother. 2013. PMID: 24060869 Free PMC article.
Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.
Long T, Neitz RJ, Beasley R, Kalyanaraman C, Suzuki BM, Jacobson MP, Dissous C, McKerrow JH, Drewry DH, Zuercher WJ, Singh R, Caffrey CR. Long T, et al. Among authors: jacobson mp. PLoS Negl Trop Dis. 2016 Jan 11;10(1):e0004356. doi: 10.1371/journal.pntd.0004356. eCollection 2016 Jan. PLoS Negl Trop Dis. 2016. PMID: 26751972 Free PMC article.
205 results