Bruno JP - Search Results

1

Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood.

Pocivavsek A, Wu HQ, Elmer GI, Bruno JP, Schwarcz R. Pocivavsek A, et al. Among authors: bruno jp. Eur J Neurosci. 2012 May;35(10):1605-12. doi: 10.1111/j.1460-9568.2012.08064.x. Epub 2012 Apr 20. Eur J Neurosci. 2012. PMID: 22515201 Free PMC article.

2

Kynurenines in the mammalian brain: when physiology meets pathology.

Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ. Schwarcz R, et al. Among authors: bruno jp. Nat Rev Neurosci. 2012 Jul;13(7):465-77. doi: 10.1038/nrn3257. Nat Rev Neurosci. 2012. PMID: 22678511 Free PMC article. Review.

3

Targeting kynurenine aminotransferase II in psychiatric diseases: promising effects of an orally active enzyme inhibitor.

Wu HQ, Okuyama M, Kajii Y, Pocivavsek A, Bruno JP, Schwarcz R. Wu HQ, et al. Among authors: bruno jp. Schizophr Bull. 2014 Mar;40 Suppl 2(Suppl 2):S152-8. doi: 10.1093/schbul/sbt157. Schizophr Bull. 2014. PMID: 24562494 Free PMC article.

4

Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats.

Pocivavsek A, Thomas MA, Elmer GI, Bruno JP, Schwarcz R. Pocivavsek A, et al. Among authors: bruno jp. Psychopharmacology (Berl). 2014 Jul;231(14):2799-809. doi: 10.1007/s00213-014-3452-2. Epub 2014 Mar 4. Psychopharmacology (Berl). 2014. PMID: 24590052 Free PMC article.

5

Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia.

Pershing ML, Bortz DM, Pocivavsek A, Fredericks PJ, Jørgensen CV, Vunck SA, Leuner B, Schwarcz R, Bruno JP. Pershing ML, et al. Among authors: bruno jp. Neuropharmacology. 2015 Mar;90:33-41. doi: 10.1016/j.neuropharm.2014.10.017. Epub 2014 Nov 1. Neuropharmacology. 2015. PMID: 25446576 Free PMC article.

6

Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding.

Pershing ML, Phenis D, Valentini V, Pocivavsek A, Lindquist DH, Schwarcz R, Bruno JP. Pershing ML, et al. Among authors: bruno jp. Psychopharmacology (Berl). 2016 Oct;233(21-22):3725-3735. doi: 10.1007/s00213-016-4404-9. Epub 2016 Aug 16. Psychopharmacology (Berl). 2016. PMID: 27527585 Free PMC article.

7

The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex.

Wu HQ, Pereira EF, Bruno JP, Pellicciari R, Albuquerque EX, Schwarcz R. Wu HQ, et al. Among authors: bruno jp. J Mol Neurosci. 2010 Jan;40(1-2):204-10. doi: 10.1007/s12031-009-9235-2. Epub 2009 Aug 19. J Mol Neurosci. 2010. PMID: 19690987 Free PMC article.

8

Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine.

Alexander KS, Pocivavsek A, Wu HQ, Pershing ML, Schwarcz R, Bruno JP. Alexander KS, et al. Among authors: bruno jp. Neuroscience. 2013 May 15;238:19-28. doi: 10.1016/j.neuroscience.2013.01.063. Epub 2013 Feb 6. Neuroscience. 2013. PMID: 23395862 Free PMC article.

9

Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine.

Alexander KS, Wu HQ, Schwarcz R, Bruno JP. Alexander KS, et al. Among authors: bruno jp. Psychopharmacology (Berl). 2012 Apr;220(3):627-37. doi: 10.1007/s00213-011-2539-2. Epub 2011 Oct 26. Psychopharmacology (Berl). 2012. PMID: 22038535 Free PMC article.

10

Preferential Disruption of Prefrontal GABAergic Function by Nanomolar Concentrations of the α7nACh Negative Modulator Kynurenic Acid.

Flores-Barrera E, Thomases DR, Cass DK, Bhandari A, Schwarcz R, Bruno JP, Tseng KY. Flores-Barrera E, et al. Among authors: bruno jp. J Neurosci. 2017 Aug 16;37(33):7921-7929. doi: 10.1523/JNEUROSCI.0932-17.2017. Epub 2017 Jul 20. J Neurosci. 2017. PMID: 28729445 Free PMC article.

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