Yang S - Search Results

1

A simple and effective method to generate lentiviral vectors for ex vivo gene delivery to mature human peripheral blood lymphocytes.

Yang S, Karne NK, Goff SL, Black MA, Xu H, Bischof D, Cornetta K, Rosenberg SA, Morgan RA, Feldman SA. Yang S, et al. Hum Gene Ther Methods. 2012 Apr;23(2):73-83. doi: 10.1089/hgtb.2011.199. Epub 2012 Apr 19. Hum Gene Ther Methods. 2012. PMID: 22515320 Free PMC article.

2

Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition.

Yang S, Cohen CJ, Peng PD, Zhao Y, Cassard L, Yu Z, Zheng Z, Jones S, Restifo NP, Rosenberg SA, Morgan RA. Yang S, et al. Gene Ther. 2008 Nov;15(21):1411-23. doi: 10.1038/gt.2008.90. Epub 2008 May 22. Gene Ther. 2008. PMID: 18496571 Free PMC article.

3

Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less-differentiated cells.

Yang S, Rosenberg SA, Morgan RA. Yang S, et al. J Immunother. 2008 Nov-Dec;31(9):830-9. doi: 10.1097/CJI.0b013e31818817c5. J Immunother. 2008. PMID: 18833004 Free PMC article.

4

Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.

Jones S, Peng PD, Yang S, Hsu C, Cohen CJ, Zhao Y, Abad J, Zheng Z, Rosenberg SA, Morgan RA. Jones S, et al. Among authors: yang s. Hum Gene Ther. 2009 Jun;20(6):630-40. doi: 10.1089/hum.2008.048. Hum Gene Ther. 2009. PMID: 19265475 Free PMC article.

5

Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.

Peng PD, Cohen CJ, Yang S, Hsu C, Jones S, Zhao Y, Zheng Z, Rosenberg SA, Morgan RA. Peng PD, et al. Among authors: yang s. Gene Ther. 2009 Aug;16(8):1042-9. doi: 10.1038/gt.2009.54. Epub 2009 Jun 4. Gene Ther. 2009. PMID: 19494842 Free PMC article.

6

A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity.

Zhao Y, Wang QJ, Yang S, Kochenderfer JN, Zheng Z, Zhong X, Sadelain M, Eshhar Z, Rosenberg SA, Morgan RA. Zhao Y, et al. Among authors: yang s. J Immunol. 2009 Nov 1;183(9):5563-74. doi: 10.4049/jimmunol.0900447. J Immunol. 2009. PMID: 19843940 Free PMC article.

7

A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.

Yang S, Dudley ME, Rosenberg SA, Morgan RA. Yang S, et al. J Immunother. 2010 Jul-Aug;33(6):648-58. doi: 10.1097/CJI.0b013e3181e311cb. J Immunother. 2010. PMID: 20551831 Free PMC article.

8

Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.

Hinrichs CS, Borman ZA, Gattinoni L, Yu Z, Burns WR, Huang J, Klebanoff CA, Johnson LA, Kerkar SP, Yang S, Muranski P, Palmer DC, Scott CD, Morgan RA, Robbins PF, Rosenberg SA, Restifo NP. Hinrichs CS, et al. Among authors: yang s. Blood. 2011 Jan 20;117(3):808-14. doi: 10.1182/blood-2010-05-286286. Epub 2010 Oct 22. Blood. 2011. PMID: 20971955 Free PMC article.

9

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.

Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, Rosenberg SA, Morgan RA. Zhang L, et al. Among authors: yang s. Mol Ther. 2011 Apr;19(4):751-9. doi: 10.1038/mt.2010.313. Epub 2011 Feb 1. Mol Ther. 2011. PMID: 21285960 Free PMC article.

10

In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells.

Yang S, Gattinoni L, Liu F, Ji Y, Yu Z, Restifo NP, Rosenberg SA, Morgan RA. Yang S, et al. Cancer Immunol Immunother. 2011 May;60(5):739-49. doi: 10.1007/s00262-011-0977-7. Epub 2011 Feb 9. Cancer Immunol Immunother. 2011. PMID: 21305379 Free PMC article.

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