Ma X - Search Results

1

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity.

Kong B, Csanaky IL, Aleksunes LM, Patni M, Chen Q, Ma X, Jaeschke H, Weir S, Broward M, Klaassen CD, Guo GL. Kong B, et al. Among authors: ma x. Toxicol Appl Pharmacol. 2012 Jun 1;261(2):189-95. doi: 10.1016/j.taap.2012.04.001. Epub 2012 Apr 11. Toxicol Appl Pharmacol. 2012. PMID: 22521610 Free PMC article.

2

The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A.

Ma X, Shah Y, Cheung C, Guo GL, Feigenbaum L, Krausz KW, Idle JR, Gonzalez FJ. Ma X, et al. Drug Metab Dispos. 2007 Feb;35(2):194-200. doi: 10.1124/dmd.106.012831. Epub 2006 Nov 8. Drug Metab Dispos. 2007. PMID: 17093002

3

Rifaximin is a gut-specific human pregnane X receptor activator.

Ma X, Shah YM, Guo GL, Wang T, Krausz KW, Idle JR, Gonzalez FJ. Ma X, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):391-8. doi: 10.1124/jpet.107.121913. Epub 2007 Apr 18. J Pharmacol Exp Ther. 2007. PMID: 17442842

4

Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice.

Li F, Wang L, Guo GL, Ma X. Li F, et al. Among authors: ma x. Drug Metab Dispos. 2010 May;38(5):871-8. doi: 10.1124/dmd.109.030817. Epub 2010 Jan 26. Drug Metab Dispos. 2010. PMID: 20103582 Free PMC article.

5

The Chinese herbal medicine Sophora flavescens activates pregnane X receptor.

Wang L, Li F, Lu J, Li G, Li D, Zhong XB, Guo GL, Ma X. Wang L, et al. Among authors: ma x. Drug Metab Dispos. 2010 Dec;38(12):2226-31. doi: 10.1124/dmd.110.035253. Epub 2010 Aug 24. Drug Metab Dispos. 2010. PMID: 20736322 Free PMC article.

6

CYP2D plays a major role in berberine metabolism in liver of mice and humans.

Guo Y, Li F, Ma X, Cheng X, Zhou H, Klaassen CD. Guo Y, et al. Among authors: ma x. Xenobiotica. 2011 Nov;41(11):996-1005. doi: 10.3109/00498254.2011.597456. Epub 2011 Jul 25. Xenobiotica. 2011. PMID: 21787170 Free PMC article.

7

Metabolomic screening and identification of the bioactivation pathways of ritonavir.

Li F, Lu J, Ma X. Li F, et al. Among authors: ma x. Chem Res Toxicol. 2011 Dec 19;24(12):2109-14. doi: 10.1021/tx2004147. Epub 2011 Nov 17. Chem Res Toxicol. 2011. PMID: 22040299 Free PMC article.

8

Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice.

Borude P, Edwards G, Walesky C, Li F, Ma X, Kong B, Guo GL, Apte U. Borude P, et al. Among authors: ma x. Hepatology. 2012 Dec;56(6):2344-52. doi: 10.1002/hep.25918. Hepatology. 2012. PMID: 22730081 Free PMC article.

9

Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy.

Li F, Lu J, Cheng J, Wang L, Matsubara T, Csanaky IL, Klaassen CD, Gonzalez FJ, Ma X. Li F, et al. Among authors: ma x. Nat Med. 2013 Apr;19(4):418-20. doi: 10.1038/nm.3104. Epub 2013 Mar 10. Nat Med. 2013. PMID: 23475203 Free PMC article.

10

Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans.

McGill MR, Li F, Sharpe MR, Williams CD, Curry SC, Ma X, Jaeschke H. McGill MR, et al. Among authors: ma x. Arch Toxicol. 2014 Feb;88(2):391-401. doi: 10.1007/s00204-013-1118-1. Epub 2013 Aug 25. Arch Toxicol. 2014. PMID: 23979652 Free PMC article.

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