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The design, synthesis, and biological evaluation of PIM kinase inhibitors.
Tsuhako AL, Brown DS, Koltun ES, Aay N, Arcalas A, Chan V, Du H, Engst S, Franzini M, Galan A, Huang P, Johnston S, Kane B, Kim MH, Laird AD, Lin R, Mock L, Ngan I, Pack M, Stott G, Stout TJ, Yu P, Zaharia C, Zhang W, Zhou P, Nuss JM, Kearney PC, Xu W. Tsuhako AL, et al. Among authors: johnston s. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3732-8. doi: 10.1016/j.bmcl.2012.04.025. Epub 2012 Apr 11. Bioorg Med Chem Lett. 2012. PMID: 22542012
Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973).
Rice KD, Aay N, Anand NK, Blazey CM, Bowles OJ, Bussenius J, Costanzo S, Curtis JK, Defina SC, Dubenko L, Engst S, Joshi AA, Kennedy AR, Kim AI, Koltun ES, Lougheed JC, Manalo JC, Martini JF, Nuss JM, Peto CJ, Tsang TH, Yu P, Johnston S. Rice KD, et al. Among authors: johnston s. ACS Med Chem Lett. 2012 Apr 9;3(5):416-21. doi: 10.1021/ml300049d. eCollection 2012 May 10. ACS Med Chem Lett. 2012. PMID: 24900486 Free PMC article.
A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors.
Rosen LS, LoRusso P, Ma WW, Goldman JW, Weise A, Colevas AD, Adjei A, Yazji S, Shen A, Johnston S, Hsieh HJ, Chan IT, Sikic BI. Rosen LS, et al. Among authors: johnston s. Invest New Drugs. 2016 Oct;34(5):604-13. doi: 10.1007/s10637-016-0374-3. Epub 2016 Jul 16. Invest New Drugs. 2016. PMID: 27424159 Free PMC article. Clinical Trial.
Adult-onset dysphagia.
Chuang F, Arasu R, Quail G, Johnston S. Chuang F, et al. Among authors: johnston s. Aust J Gen Pract. 2024 Dec-Supplement;53(12 Suppl):S33-S40. doi: 10.31128/AJGP-08-23-6928. Aust J Gen Pract. 2024. PMID: 39693748 Free article.
GaAs Solar Cells Grown Directly on V-Groove Si Substrates.
Saenz TE, Boyer J, Mangum JS, Neumann AN, Selvidge J, Collins SA, Young MS, Johnston SW, Steiner MA, France RM, McMahon WE, Zimmerman JD, Warren EL. Saenz TE, et al. Among authors: johnston sw. ACS Appl Mater Interfaces. 2024 Dec 18. doi: 10.1021/acsami.4c18928. Online ahead of print. ACS Appl Mater Interfaces. 2024. PMID: 39693576
3,405 results