Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.
Bouybayoune I, Mantovani S, Del Gallo F, Bertani I, Restelli E, Comerio L, Tapella L, Baracchi F, Fernández-Borges N, Mangieri M, Bisighini C, Beznoussenko GV, Paladini A, Balducci C, Micotti E, Forloni G, Castilla J, Fiordaliso F, Tagliavini F, Imeri L, Chiesa R.
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PLoS Pathog. 2015 Apr 16;11(4):e1004796. doi: 10.1371/journal.ppat.1004796. eCollection 2015 Apr.
PLoS Pathog. 2015.
PMID: 25880443
Free PMC article.