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5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals.
Sisignano M, Park CK, Angioni C, Zhang DD, von Hehn C, Cobos EJ, Ghasemlou N, Xu ZZ, Kumaran V, Lu R, Grant A, Fischer MJ, Schmidtko A, Reeh P, Ji RR, Woolf CJ, Geisslinger G, Scholich K, Brenneis C. Sisignano M, et al. Among authors: ji rr. J Neurosci. 2012 May 2;32(18):6364-72. doi: 10.1523/JNEUROSCI.5793-11.2012. J Neurosci. 2012. PMID: 22553041 Free PMC article.
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E, Woolf CJ. Samad TA, et al. Among authors: ji rr. J Neurosci. 2004 Feb 25;24(8):2027-36. doi: 10.1523/JNEUROSCI.4115-03.2004. J Neurosci. 2004. PMID: 14985445 Free PMC article.
274 results