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Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases.
Böing I, Stross C, Radtke S, Lippok BE, Heinrich PC, Hermanns HM. Böing I, et al. Among authors: radtke s. Cell Signal. 2006 Jan;18(1):50-61. doi: 10.1016/j.cellsig.2005.03.015. Epub 2005 Jun 1. Cell Signal. 2006. PMID: 15935618
Interestingly, activation of p38 and JNK originates from tyrosine residue 861 in the OSMR; the same tyrosine residue which we identified before to be involved in the activation of the mitogen-activated kinases Erk1/2 [Hermanns, H. M., Radtke, S., Schaper, F., Heinri …
Interestingly, activation of p38 and JNK originates from tyrosine residue 861 in the OSMR; the same tyrosine residue which we identified bef …
127 results