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457 results

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Page 1
Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors.
de Wilde RF, Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE. de Wilde RF, et al. Among authors: offerhaus gj. Mod Pathol. 2012 Jul;25(7):1033-9. doi: 10.1038/modpathol.2012.53. Epub 2012 May 11. Mod Pathol. 2012. PMID: 22575867 Free PMC article.
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia.
van Heek NT, Meeker AK, Kern SE, Yeo CJ, Lillemoe KD, Cameron JL, Offerhaus GJ, Hicks JL, Wilentz RE, Goggins MG, De Marzo AM, Hruban RH, Maitra A. van Heek NT, et al. Among authors: offerhaus gj. Am J Pathol. 2002 Nov;161(5):1541-7. doi: 10.1016/S0002-9440(10)64432-X. Am J Pathol. 2002. PMID: 12414502 Free PMC article.
Whole-exome sequencing of pancreatic neoplasms with acinar differentiation.
Jiao Y, Yonescu R, Offerhaus GJ, Klimstra DS, Maitra A, Eshleman JR, Herman JG, Poh W, Pelosof L, Wolfgang CL, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N, Wood LD. Jiao Y, et al. Among authors: offerhaus gj. J Pathol. 2014 Mar;232(4):428-35. doi: 10.1002/path.4310. J Pathol. 2014. PMID: 24293293 Free PMC article.
Genetic Analysis of Small Well-differentiated Pancreatic Neuroendocrine Tumors Identifies Subgroups With Differing Risks of Liver Metastases.
Pea A, Yu J, Marchionni L, Noe M, Luchini C, Pulvirenti A, de Wilde RF, Brosens LA, Rezaee N, Javed A, Chianchiano P, Gobbo S, Regi P, Salvia R, Bassi C, He J, Weiss MJ, Cameron JL, Offerhaus GJA, Hruban RH, Lawlor RT, Scarpa A, Heaphy CM, Wood LD, Wolfgang CL. Pea A, et al. Ann Surg. 2020 Mar;271(3):566-573. doi: 10.1097/SLA.0000000000003022. Ann Surg. 2020. PMID: 30339629 Free PMC article.
Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas.
Hackeng WM, Schelhaas W, Morsink FHM, Heidsma CM, van Eeden S, Valk GD, Vriens MR, Heaphy CM, Nieveen van Dijkum EJM, Offerhaus GJA, Dreijerink KMA, Brosens LAA. Hackeng WM, et al. Endocr Pathol. 2020 Jun;31(2):108-118. doi: 10.1007/s12022-020-09611-8. Endocr Pathol. 2020. PMID: 32103422 Free PMC article.
Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size.
Hackeng WM, Brosens LAA, Kim JY, O'Sullivan R, Sung YN, Liu TC, Cao D, Heayn M, Brosnan-Cashman J, An S, Morsink FHM, Heidsma CM, Valk GD, Vriens MR, Nieveen van Dijkum E, Offerhaus GJA, Dreijerink KMA, Zeh H, Zureikat AH, Hogg M, Lee K, Geller D, Marsh JW, Paniccia A, Ongchin M, Pingpank JF, Bahary N, Aijazi M, Brand R, Chennat J, Das R, Fasanella KE, Khalid A, McGrath K, Sarkaria S, Singh H, Slivka A, Nalesnik M, Han X, Nikiforova MN, Lawlor RT, Mafficini A, Rusev B, Corbo V, Luchini C, Bersani S, Pea A, Cingarlini S, Landoni L, Salvia R, Milione M, Milella M, Scarpa A, Hong SM, Heaphy CM, Singhi AD. Hackeng WM, et al. Gut. 2022 May;71(5):961-973. doi: 10.1136/gutjnl-2020-322595. Epub 2021 Apr 13. Gut. 2022. PMID: 33849943 Free PMC article.
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.
Wu J, Jiao Y, Dal Molin M, Maitra A, de Wilde RF, Wood LD, Eshleman JR, Goggins MG, Wolfgang CL, Canto MI, Schulick RD, Edil BH, Choti MA, Adsay V, Klimstra DS, Offerhaus GJ, Klein AP, Kopelovich L, Carter H, Karchin R, Allen PJ, Schmidt CM, Naito Y, Diaz LA Jr, Kinzler KW, Papadopoulos N, Hruban RH, Vogelstein B. Wu J, et al. Among authors: offerhaus gj. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21188-93. doi: 10.1073/pnas.1118046108. Epub 2011 Dec 8. Proc Natl Acad Sci U S A. 2011. PMID: 22158988 Free PMC article.
Surgical and molecular pathology of pancreatic neoplasms.
Hackeng WM, Hruban RH, Offerhaus GJ, Brosens LA. Hackeng WM, et al. Among authors: offerhaus gj. Diagn Pathol. 2016 Jun 7;11(1):47. doi: 10.1186/s13000-016-0497-z. Diagn Pathol. 2016. PMID: 27267993 Free PMC article. Review.
457 results