Hare S - Search Results

1

3'-processing and strand transfer catalysed by retroviral integrase in crystallo.

Hare S, Maertens GN, Cherepanov P. Hare S, et al. EMBO J. 2012 Jun 29;31(13):3020-8. doi: 10.1038/emboj.2012.118. Epub 2012 May 11. EMBO J. 2012. PMID: 22580823 Free PMC article.

2

Functional and structural characterization of the integrase from the prototype foamy virus.

Valkov E, Gupta SS, Hare S, Helander A, Roversi P, McClure M, Cherepanov P. Valkov E, et al. Among authors: hare s. Nucleic Acids Res. 2009 Jan;37(1):243-55. doi: 10.1093/nar/gkn938. Epub 2008 Nov 26. Nucleic Acids Res. 2009. PMID: 19036793 Free PMC article.

3

Structural basis for functional tetramerization of lentiviral integrase.

Hare S, Di Nunzio F, Labeja A, Wang J, Engelman A, Cherepanov P. Hare S, et al. PLoS Pathog. 2009 Jul;5(7):e1000515. doi: 10.1371/journal.ppat.1000515. Epub 2009 Jul 17. PLoS Pathog. 2009. PMID: 19609359 Free PMC article.

4

Retroviral intasome assembly and inhibition of DNA strand transfer.

Hare S, Gupta SS, Valkov E, Engelman A, Cherepanov P. Hare S, et al. Nature. 2010 Mar 11;464(7286):232-6. doi: 10.1038/nature08784. Epub 2010 Jan 31. Nature. 2010. PMID: 20118915 Free PMC article.

5

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.

Hare S, Vos AM, Clayton RF, Thuring JW, Cummings MD, Cherepanov P. Hare S, et al. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20057-62. doi: 10.1073/pnas.1010246107. Epub 2010 Oct 28. Proc Natl Acad Sci U S A. 2010. PMID: 21030679 Free PMC article.

6

The mechanism of retroviral integration from X-ray structures of its key intermediates.

Maertens GN, Hare S, Cherepanov P. Maertens GN, et al. Among authors: hare s. Nature. 2010 Nov 11;468(7321):326-9. doi: 10.1038/nature09517. Nature. 2010. PMID: 21068843 Free PMC article.

7

Structural insights into the retroviral DNA integration apparatus.

Cherepanov P, Maertens GN, Hare S. Cherepanov P, et al. Among authors: hare s. Curr Opin Struct Biol. 2011 Apr;21(2):249-56. doi: 10.1016/j.sbi.2010.12.005. Epub 2011 Feb 1. Curr Opin Struct Biol. 2011. PMID: 21277766 Review.

8

Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572).

Hare S, Smith SJ, Métifiot M, Jaxa-Chamiec A, Pommier Y, Hughes SH, Cherepanov P. Hare S, et al. Mol Pharmacol. 2011 Oct;80(4):565-72. doi: 10.1124/mol.111.073189. Epub 2011 Jun 30. Mol Pharmacol. 2011. PMID: 21719464 Free PMC article.

9

Structural basis for retroviral integration into nucleosomes.

Maskell DP, Renault L, Serrao E, Lesbats P, Matadeen R, Hare S, Lindemann D, Engelman AN, Costa A, Cherepanov P. Maskell DP, et al. Among authors: hare s. Nature. 2015 Jul 16;523(7560):366-9. doi: 10.1038/nature14495. Epub 2015 Jun 10. Nature. 2015. PMID: 26061770 Free PMC article.

10

A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75.

Hare S, Shun MC, Gupta SS, Valkov E, Engelman A, Cherepanov P. Hare S, et al. PLoS Pathog. 2009 Jan;5(1):e1000259. doi: 10.1371/journal.ppat.1000259. Epub 2009 Jan 9. PLoS Pathog. 2009. PMID: 19132083 Free PMC article.

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