Roberts KD - Search Results

1

Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein.

Azad MA, Huang JX, Cooper MA, Roberts KD, Thompson PE, Nation RL, Li J, Velkov T. Azad MA, et al. Among authors: roberts kd. Biochem Pharmacol. 2012 Aug 1;84(3):278-91. doi: 10.1016/j.bcp.2012.05.004. Epub 2012 May 12. Biochem Pharmacol. 2012. PMID: 22587817 Free PMC article.

2

Design, synthesis, and evaluation of a new fluorescent probe for measuring polymyxin-lipopolysaccharide binding interactions.

Soon RL, Velkov T, Chiu F, Thompson PE, Kancharla R, Roberts K, Larson I, Nation RL, Li J. Soon RL, et al. Anal Biochem. 2011 Feb 15;409(2):273-83. doi: 10.1016/j.ab.2010.10.033. Epub 2010 Nov 2. Anal Biochem. 2011. PMID: 21050838 Free PMC article.

3

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

Velkov T, Soon RL, Chong PL, Huang JX, Cooper MA, Azad MA, Baker MA, Thompson PE, Roberts K, Nation RL, Clements A, Strugnell RA, Li J. Velkov T, et al. Innate Immun. 2013 Jun;19(3):265-77. doi: 10.1177/1753425912459092. Epub 2012 Sep 24. Innate Immun. 2013. PMID: 23008349 Free PMC article.

4

Pharmacology of polymyxins: new insights into an 'old' class of antibiotics.

Velkov T, Roberts KD, Nation RL, Thompson PE, Li J. Velkov T, et al. Among authors: roberts kd. Future Microbiol. 2013 Jun;8(6):711-24. doi: 10.2217/fmb.13.39. Future Microbiol. 2013. PMID: 23701329 Free PMC article. Review.

5

Pharmacokinetics of four different brands of colistimethate and formed colistin in rats.

He H, Li JC, Nation RL, Jacob J, Chen G, Lee HJ, Tsuji BT, Thompson PE, Roberts K, Velkov T, Li J. He H, et al. J Antimicrob Chemother. 2013 Oct;68(10):2311-7. doi: 10.1093/jac/dkt207. Epub 2013 Jun 7. J Antimicrob Chemother. 2013. PMID: 23749953 Free PMC article.

6

Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro.

McCoy LS, Roberts KD, Nation RL, Thompson PE, Velkov T, Li J, Tor Y. McCoy LS, et al. Among authors: roberts kd. Chembiochem. 2013 Nov 4;14(16):2083-6. doi: 10.1002/cbic.201300496. Epub 2013 Sep 18. Chembiochem. 2013. PMID: 24105917 Free PMC article.

7

A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity.

Deris ZZ, Akter J, Sivanesan S, Roberts KD, Thompson PE, Nation RL, Li J, Velkov T. Deris ZZ, et al. Among authors: roberts kd. J Antibiot (Tokyo). 2014 Feb;67(2):147-51. doi: 10.1038/ja.2013.111. Epub 2013 Oct 30. J Antibiot (Tokyo). 2014. PMID: 24169795 Free PMC article.

8

Teaching 'old' polymyxins new tricks: new-generation lipopeptides targeting gram-negative 'superbugs'.

Velkov T, Roberts KD, Nation RL, Wang J, Thompson PE, Li J. Velkov T, et al. Among authors: roberts kd. ACS Chem Biol. 2014 May 16;9(5):1172-7. doi: 10.1021/cb500080r. Epub 2014 Mar 17. ACS Chem Biol. 2014. PMID: 24601489 Free PMC article.

9

Probing the penetration of antimicrobial polymyxin lipopeptides into gram-negative bacteria.

Deris ZZ, Swarbrick JD, Roberts KD, Azad MA, Akter J, Horne AS, Nation RL, Rogers KL, Thompson PE, Velkov T, Li J. Deris ZZ, et al. Among authors: roberts kd. Bioconjug Chem. 2014 Apr 16;25(4):750-60. doi: 10.1021/bc500094d. Epub 2014 Mar 27. Bioconjug Chem. 2014. PMID: 24635310 Free PMC article.

10

Measuring polymyxin uptake by renal tubular cells: is BODIPY-polymyxin B an appropriate probe?

Azad MA, Yun B, Roberts KD, Nation RL, Thompson PE, Velkov T, Li J. Azad MA, et al. Among authors: roberts kd. Antimicrob Agents Chemother. 2014 Oct;58(10):6337-8. doi: 10.1128/AAC.03733-14. Antimicrob Agents Chemother. 2014. PMID: 25225340 Free PMC article. No abstract available.

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