McCay PB - Search Results

1

Iron-mediated radical reactions upon reperfusion contribute to myocardial "stunning".

Bolli R, Patel BS, Jeroudi MO, Li XY, Triana JF, Lai EK, McCay PB. Bolli R, et al. Among authors: mccay pb. Am J Physiol. 1990 Dec;259(6 Pt 2):H1901-11. doi: 10.1152/ajpheart.1990.259.6.H1901. Am J Physiol. 1990. PMID: 2260714

2

Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

Bolli R, Jeroudi MO, Patel BS, DuBose CM, Lai EK, Roberts R, McCay PB. Bolli R, et al. Among authors: mccay pb. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4695-9. doi: 10.1073/pnas.86.12.4695. Proc Natl Acad Sci U S A. 1989. PMID: 2543984 Free PMC article.

3

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury.

Bolli R, Jeroudi MO, Patel BS, Aruoma OI, Halliwell B, Lai EK, McCay PB. Bolli R, et al. Among authors: mccay pb. Circ Res. 1989 Sep;65(3):607-22. doi: 10.1161/01.res.65.3.607. Circ Res. 1989. PMID: 2548761

4

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

Bolli R, Patel BS, Jeroudi MO, Lai EK, McCay PB. Bolli R, et al. Among authors: mccay pb. J Clin Invest. 1988 Aug;82(2):476-85. doi: 10.1172/JCI113621. J Clin Invest. 1988. PMID: 2841353 Free PMC article.

5

Recurrent ischemia in the canine heart causes recurrent bursts of free radical production that have a cumulative effect on contractile function. A pathophysiological basis for chronic myocardial "stunning".

Bolli R, Zughaib M, Li XY, Tang XL, Sun JZ, Triana JF, McCay PB. Bolli R, et al. Among authors: mccay pb. J Clin Invest. 1995 Aug;96(2):1066-84. doi: 10.1172/JCI118093. J Clin Invest. 1995. PMID: 7635943 Free PMC article.

6

Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

Li XY, McCay PB, Zughaib M, Jeroudi MO, Triana JF, Bolli R. Li XY, et al. Among authors: mccay pb. J Clin Invest. 1993 Aug;92(2):1025-41. doi: 10.1172/JCI116608. J Clin Invest. 1993. PMID: 8394382 Free PMC article.

7

Direct evidence that the hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects.

Sekili S, McCay PB, Li XY, Zughaib M, Sun JZ, Tang L, Thornby JI, Bolli R. Sekili S, et al. Among authors: mccay pb. Circ Res. 1993 Oct;73(4):705-23. doi: 10.1161/01.res.73.4.705. Circ Res. 1993. PMID: 8396504

8

Use of spin traps in intact animals undergoing myocardial ischemia/reperfusion: a new approach to assessing the role of oxygen radicals in myocardial "stunning".

Bolli R, McCay PB. Bolli R, et al. Among authors: mccay pb. Free Radic Res Commun. 1990;9(3-6):169-80. doi: 10.3109/10715769009145674. Free Radic Res Commun. 1990. PMID: 2167254

9

Inhibitory effect of a hydrophilic alpha-tocopherol analogue, MDL 74,405, on generation of free radicals in stunned myocardium in dogs.

Tang XL, McCay PB, Sun JZ, Hartley CJ, Schleman M, Bolli R. Tang XL, et al. Among authors: mccay pb. Free Radic Res. 1995 Apr;22(4):293-302. doi: 10.3109/10715769509145641. Free Radic Res. 1995. PMID: 7633559

10

Lack of myocardial lipid peroxidation during acute reperfusion injury in perfused guinea pig hearts.

Barrington PL, Lai E, McCay PB. Barrington PL, et al. Among authors: mccay pb. Cardiovasc Res. 1993 Jul;27(7):1339-45. doi: 10.1093/cvr/27.7.1339. Cardiovasc Res. 1993. PMID: 8252597

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