van Benthem J - Search Results

1

Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro.

Zwart EP, Schaap MM, van den Dungen MW, Braakhuis HM, White PA, van Steeg H, van Benthem J, Luijten M. Zwart EP, et al. Among authors: van den dungen mw, van steeg h, van benthem j. Environ Mol Mutagen. 2012 Jun;53(5):1-8. doi: 10.1002/em.21700. Epub 2012 May 23. Environ Mol Mutagen. 2012. PMID: 22619112

2

lacZ mouse embryonic fibroblasts detect both clastogens and mutagens.

Mahabir AG, Zwart E, Schaap M, van Benthem J, de Vries A, Hernandez LG, Hendriksen CF, van Steeg H. Mahabir AG, et al. Among authors: van steeg h, van benthem j. Mutat Res. 2009 Jun 18;666(1-2):50-6. doi: 10.1016/j.mrfmmm.2009.04.005. Epub 2009 Apr 23. Mutat Res. 2009. PMID: 19393670

3

Can carcinogenic potency be predicted from in vivo genotoxicity data?: a meta-analysis of historical data.

Hernández LG, Slob W, van Steeg H, van Benthem J. Hernández LG, et al. Among authors: van steeg h, van benthem j. Environ Mol Mutagen. 2011 Aug;52(7):518-28. doi: 10.1002/em.20651. Epub 2011 May 3. Environ Mol Mutagen. 2011. PMID: 21542028

4

Evaluation of the LacZ reporter assay in cryopreserved primary hepatocytes for In vitro genotoxicity testing.

Luijten M, Zwart EP, Dollé ME, de Pooter M, Cox JA, White PA, van Benthem J. Luijten M, et al. Among authors: van benthem j. Environ Mol Mutagen. 2016 Dec;57(9):643-655. doi: 10.1002/em.22063. Epub 2016 Nov 9. Environ Mol Mutagen. 2016. PMID: 27859631

5

Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene.

Luijten M, Ball NS, Dearfield KL, Gollapudi BB, Johnson GE, Madia F, Peel L, Pfuhler S, Settivari RS, Ter Burg W, White PA, van Benthem J. Luijten M, et al. Among authors: van benthem j. Environ Mol Mutagen. 2020 Jan;61(1):94-113. doi: 10.1002/em.22346. Epub 2019 Nov 27. Environ Mol Mutagen. 2020. PMID: 31709603 Free PMC article. Review.

6

Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice.

Luijten M, Speksnijder EN, van Alphen N, Westerman A, Heisterkamp SH, van Benthem J, van Kreijl CF, Beems RB, van Steeg H. Luijten M, et al. Among authors: van alphen n, van kreijl cf, van steeg h, van benthem j. Mutat Res. 2006 Apr 11;596(1-2):143-50. doi: 10.1016/j.mrfmmm.2005.12.011. Epub 2006 Feb 7. Mutat Res. 2006. PMID: 16464479

7

Detecting genotoxic effects of potential clastogens: an in vivo study using the transgenic lacZ plasmid and the MutaMouse model.

Mahabir AG, van Benthem J, Korsten H, Lynch AM, Bailey L, de Vries A, Hendriksen CF, van Steeg H. Mahabir AG, et al. Among authors: van steeg h, van benthem j. Mutat Res. 2008 Apr 30;652(2):151-7. doi: 10.1016/j.mrgentox.2008.01.007. Epub 2008 Feb 23. Mutat Res. 2008. PMID: 18387846

8

DNA-repair-deficient Rad54/Rad54B mice are more sensitive to clastogens than wild-type mice.

Mahabir AG, Schaap M, Theunissen P, van Benthem J, Essers J, de Vries A, Hendriksen CF, van Steeg H. Mahabir AG, et al. Among authors: van steeg h, van benthem j. Toxicol Lett. 2008 Dec 15;183(1-3):112-7. doi: 10.1016/j.toxlet.2008.10.005. Epub 2008 Oct 21. Toxicol Lett. 2008. PMID: 19007869

9

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach.

Hernández LG, van Steeg H, Luijten M, van Benthem J. Hernández LG, et al. Among authors: van steeg h, van benthem j. Mutat Res. 2009 Sep-Dec;682(2-3):94-109. doi: 10.1016/j.mrrev.2009.07.002. Epub 2009 Jul 22. Mutat Res. 2009. PMID: 19631282 Review.

10

DNA adduct kinetics in reproductive tissues of DNA repair proficient and deficient male mice after oral exposure to benzo(a)pyrene.

Verhofstad N, van Oostrom CT, van Benthem J, van Schooten FJ, van Steeg H, Godschalk RW. Verhofstad N, et al. Among authors: van steeg h, van schooten fj, van benthem j, van oostrom ct. Environ Mol Mutagen. 2010 Mar;51(2):123-9. doi: 10.1002/em.20516. Environ Mol Mutagen. 2010. PMID: 19634154 Free article.

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