Tymiak A - Search Results

1

A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies.

Furlong MT, Ouyang Z, Wu S, Tamura J, Olah T, Tymiak A, Jemal M. Furlong MT, et al. Among authors: tymiak a. Biomed Chromatogr. 2012 Aug;26(8):1024-32. doi: 10.1002/bmc.2759. Epub 2012 May 24. Biomed Chromatogr. 2012. PMID: 22623136

2

Pellet digestion: a simple and efficient sample preparation technique for LC-MS/MS quantification of large therapeutic proteins in plasma.

Ouyang Z, Furlong MT, Wu S, Sleczka B, Tamura J, Wang H, Suchard S, Suri A, Olah T, Tymiak A, Jemal M. Ouyang Z, et al. Among authors: tymiak a. Bioanalysis. 2012 Jan;4(1):17-28. doi: 10.4155/bio.11.286. Bioanalysis. 2012. PMID: 22191591

3

Dual universal peptide approach to bioanalysis of human monoclonal antibody protein drug candidates in animal studies.

Furlong MT, Zhao S, Mylott W, Jenkins R, Gao M, Hegde V, Tamura J, Tymiak A, Jemal M. Furlong MT, et al. Among authors: tymiak a. Bioanalysis. 2013 Jun;5(11):1363-76. doi: 10.4155/bio.13.55. Bioanalysis. 2013. PMID: 23742306

4

Quantitation of therapeutic proteins following direct trypsin digestion of dried blood spot samples and detection by LC-MS-based bioanalytical methods in drug discovery.

Sleczka BG, D'Arienzo CJ, Tymiak AA, Olah TV. Sleczka BG, et al. Among authors: tymiak aa. Bioanalysis. 2012 Jan;4(1):29-40. doi: 10.4155/bio.11.293. Bioanalysis. 2012. PMID: 22191592

5

Quantification of 4-beta-hydroxycholesterol in human plasma using automated sample preparation and LC-ESI-MS/MS analysis.

Goodenough AK, Onorato JM, Ouyang Z, Chang S, Rodrigues AD, Kasichayanula S, Huang SP, Turley W, Burrell R, Bifano M, Jemal M, LaCreta F, Tymiak A, Wang-Iverson D. Goodenough AK, et al. Among authors: tymiak a. Chem Res Toxicol. 2011 Sep 19;24(9):1575-85. doi: 10.1021/tx2001898. Epub 2011 Jul 21. Chem Res Toxicol. 2011. PMID: 21728364

6

LC-MS/MS multiplexed assay for the quantitation of a therapeutic protein BMS-986089 and the target protein Myostatin.

Zhu Y, D'Arienzo C, Lou Z, Kozhich A, Madireddi M, Chimalakonda A, Tymiak A, Olah TV. Zhu Y, et al. Among authors: tymiak a. Bioanalysis. 2016 Feb;8(3):193-204. doi: 10.4155/bio.15.238. Epub 2016 Jan 26. Bioanalysis. 2016. PMID: 26811930

7

Development of a highly sensitive liquid chromatography/tandem mass spectrometry method to quantify total and free levels of a target protein, interferon-gamma-inducible protein-10, at picomolar levels in human serum.

Zhang H, Xiao Q, Xin B, Trigona W, Tymiak AA, Dongre AR, Olah TV. Zhang H, et al. Among authors: tymiak aa. Rapid Commun Mass Spectrom. 2014 Jul 15;28(13):1535-43. doi: 10.1002/rcm.6928. Rapid Commun Mass Spectrom. 2014. PMID: 24861605

8

Approach to evaluating dried blood spot sample stability during drying process and discovery of a treated card to maintain analyte stability by rapid on-card pH modification.

Liu G, Ji QC, Jemal M, Tymiak AA, Arnold ME. Liu G, et al. Among authors: tymiak aa. Anal Chem. 2011 Dec 1;83(23):9033-8. doi: 10.1021/ac2023876. Epub 2011 Nov 1. Anal Chem. 2011. PMID: 21995953

9

Attribution of the discrepancy between ELISA and LC-MS/MS assay results of a PEGylated scaffold protein in post-dose monkey plasma samples due to the presence of anti-drug antibodies.

Wang SJ, Wu ST, Gokemeijer J, Fura A, Krishna M, Morin P, Chen G, Price K, Wang-Iverson D, Olah T, Weiner R, Tymiak A, Jemal M. Wang SJ, et al. Among authors: tymiak a. Anal Bioanal Chem. 2012 Jan;402(3):1229-39. doi: 10.1007/s00216-011-5527-9. Epub 2011 Dec 1. Anal Bioanal Chem. 2012. PMID: 22130720

10

High-throughput chiral analysis of albuterol enantiomers in dog plasma using on-line sample extraction/polar organic mode chiral liquid chromatography with tandem mass spectrometric detection.

Wu ST, Xing J, Apedo A, Wang-Iverson DB, Olah TV, Tymiak AA, Zhao N. Wu ST, et al. Among authors: tymiak aa. Rapid Commun Mass Spectrom. 2004;18(21):2531-6. doi: 10.1002/rcm.1655. Rapid Commun Mass Spectrom. 2004. PMID: 15468103

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