Sirnes S - Search Results

1

Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43.

Fykerud TA, Kjenseth A, Schink KO, Sirnes S, Bruun J, Omori Y, Brech A, Rivedal E, Leithe E. Fykerud TA, et al. Among authors: sirnes s. J Cell Sci. 2012 Sep 1;125(Pt 17):3966-76. doi: 10.1242/jcs.093500. Epub 2012 May 23. J Cell Sci. 2012. PMID: 22623726

2

Downregulation of gap junctions in cancer cells.

Leithe E, Sirnes S, Omori Y, Rivedal E. Leithe E, et al. Among authors: sirnes s. Crit Rev Oncog. 2006 Dec;12(3-4):225-56. doi: 10.1615/critrevoncog.v12.i3-4.30. Crit Rev Oncog. 2006. PMID: 17425504 Review.

3

The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis.

Sirnes S, Leithe E, Rivedal E. Sirnes S, et al. Biochem Biophys Res Commun. 2008 Sep 5;373(4):597-601. doi: 10.1016/j.bbrc.2008.06.095. Epub 2008 Jul 2. Biochem Biophys Res Commun. 2008. PMID: 18601906

4

Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication.

Sirnes S, Kjenseth A, Leithe E, Rivedal E. Sirnes S, et al. Biochem Biophys Res Commun. 2009 Apr 24;382(1):41-5. doi: 10.1016/j.bbrc.2009.02.141. Epub 2009 Mar 1. Biochem Biophys Res Commun. 2009. PMID: 19258009

5

Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101.

Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E. Leithe E, et al. Among authors: sirnes s. J Cell Sci. 2009 Nov 1;122(Pt 21):3883-93. doi: 10.1242/jcs.053801. Epub 2009 Oct 6. J Cell Sci. 2009. PMID: 19808888

6

Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil.

Leithe E, Kjenseth A, Bruun J, Sirnes S, Rivedal E. Leithe E, et al. Among authors: sirnes s. Toxicol Appl Pharmacol. 2010 Aug 15;247(1):10-7. doi: 10.1016/j.taap.2010.05.006. Epub 2010 May 25. Toxicol Appl Pharmacol. 2010. PMID: 20510257

7

Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome.

Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E. Sirnes S, et al. Int J Cancer. 2012 Aug 1;131(3):570-81. doi: 10.1002/ijc.26392. Epub 2011 Oct 20. Int J Cancer. 2012. PMID: 21866551

8

Endocytosis and post-endocytic sorting of connexins.

Leithe E, Sirnes S, Fykerud T, Kjenseth A, Rivedal E. Leithe E, et al. Among authors: sirnes s. Biochim Biophys Acta. 2012 Aug;1818(8):1870-9. doi: 10.1016/j.bbamem.2011.09.029. Epub 2011 Oct 4. Biochim Biophys Acta. 2012. PMID: 21996040 Free article. Review.

9

The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation.

Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E. Kjenseth A, et al. Among authors: sirnes s. J Biol Chem. 2012 May 4;287(19):15851-61. doi: 10.1074/jbc.M111.281832. Epub 2012 Mar 12. J Biol Chem. 2012. PMID: 22411987 Free PMC article.

10

DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer.

Sirnes S, Honne H, Ahmed D, Danielsen SA, Rognum TO, Meling GI, Leithe E, Rivedal E, Lothe RA, Lind GE. Sirnes S, et al. Epigenetics. 2011 May;6(5):602-9. doi: 10.4161/epi.6.5.15237. Epub 2011 May 1. Epigenetics. 2011. PMID: 21406965 Free article.

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