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Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.
den Hollander J, Rimpi S, Doherty JR, Rudelius M, Buck A, Hoellein A, Kremer M, Graf N, Scheerer M, Hall MA, Goga A, von Bubnoff N, Duyster J, Peschel C, Cleveland JL, Nilsson JA, Keller U. den Hollander J, et al. Among authors: hoellein a. Blood. 2010 Sep 2;116(9):1498-505. doi: 10.1182/blood-2009-11-251074. Epub 2010 Jun 2. Blood. 2010. PMID: 20519624 Free PMC article.
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Hoellein A, Fallahi M, Schoeffmann S, Steidle S, Schaub FX, Rudelius M, Laitinen I, Nilsson L, Goga A, Peschel C, Nilsson JA, Cleveland JL, Keller U. Hoellein A, et al. Blood. 2014 Sep 25;124(13):2081-90. doi: 10.1182/blood-2014-06-584524. Epub 2014 Aug 20. Blood. 2014. PMID: 25143484 Free PMC article.
38 results