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Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Ostrov DA, Grant BJ, Pompeu YA, Sidney J, Harndahl M, Southwood S, Oseroff C, Lu S, Jakoncic J, de Oliveira CA, Yang L, Mei H, Shi L, Shabanowitz J, English AM, Wriston A, Lucas A, Phillips E, Mallal S, Grey HM, Sette A, Hunt DF, Buus S, Peters B. Ostrov DA, et al. Among authors: lucas a. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9959-64. doi: 10.1073/pnas.1207934109. Epub 2012 May 29. Proc Natl Acad Sci U S A. 2012. PMID: 22645359 Free PMC article.
Abacavir-reactive memory T cells are present in drug naïve individuals.
Lucas A, Lucas M, Strhyn A, Keane NM, McKinnon E, Pavlos R, Moran EM, Meyer-Pannwitt V, Gaudieri S, D'Orsogna L, Kalams S, Ostrov DA, Buus S, Peters B, Mallal S, Phillips E. Lucas A, et al. Among authors: lucas m. PLoS One. 2015 Feb 12;10(2):e0117160. doi: 10.1371/journal.pone.0117160. eCollection 2015. PLoS One. 2015. PMID: 25674793 Free PMC article.
Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity.
Metushi IG, Wriston A, Banerjee P, Gohlke BO, English AM, Lucas A, Moore C, Sidney J, Buus S, Ostrov DA, Mallal S, Phillips E, Shabanowitz J, Hunt DF, Preissner R, Peters B. Metushi IG, et al. Among authors: lucas a. PLoS One. 2015 May 29;10(5):e0124878. doi: 10.1371/journal.pone.0124878. eCollection 2015. PLoS One. 2015. PMID: 26024233 Free PMC article.
Cytokine profiling in abacavir hypersensitivity patients.
Almeida CA, Martin AM, Nolan D, Lucas A, Cameron PU, James I, Phillips E, Mallal S. Almeida CA, et al. Among authors: lucas a. Antivir Ther. 2008;13(2):281-8. Antivir Ther. 2008. PMID: 18505179
Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity.
Kostenko L, Kjer-Nielsen L, Nicholson I, Hudson F, Lucas A, Foley B, Chen K, Lynch K, Nguyen J, Wu AH, Tait BD, Holdsworth R, Mallal S, Rossjohn J, Bharadwaj M, McCluskey J. Kostenko L, et al. Among authors: lucas a. Tissue Antigens. 2011 Jul;78(1):11-20. doi: 10.1111/j.1399-0039.2011.01649.x. Epub 2011 Apr 19. Tissue Antigens. 2011. PMID: 21501118
1,988 results