Trobridge GD - Search Results

1

Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities.

Adair JE, Zhao X, Chien S, Fang M, Wohlfahrt ME, Trobridge GD, Taylor JA, Beard BC, Kiem HP, Becker PS. Adair JE, et al. Among authors: trobridge gd. J Mol Med (Berl). 2012 Nov;90(11):1283-94. doi: 10.1007/s00109-012-0905-0. Epub 2012 Jun 3. J Mol Med (Berl). 2012. PMID: 22660274 Free PMC article.

2

Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.

Adair JE, Waters T, Haworth KG, Kubek SP, Trobridge GD, Hocum JD, Heimfeld S, Kiem HP. Adair JE, et al. Among authors: trobridge gd. Nat Commun. 2016 Oct 20;7:13173. doi: 10.1038/ncomms13173. Nat Commun. 2016. PMID: 27762266 Free PMC article.

3

Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector.

Becker PS, Taylor JA, Trobridge GD, Zhao X, Beard BC, Chien S, Adair J, Kohn DB, Wagner JE, Shimamura A, Kiem HP. Becker PS, et al. Among authors: trobridge gd. Gene Ther. 2010 Oct;17(10):1244-52. doi: 10.1038/gt.2010.62. Epub 2010 May 20. Gene Ther. 2010. PMID: 20485382 Free PMC article.

4

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients.

Beard BC, Sud R, Keyser KA, Ironside C, Neff T, Gerull S, Trobridge GD, Kiem HP. Beard BC, et al. Among authors: trobridge gd. Blood. 2009 May 21;113(21):5094-103. doi: 10.1182/blood-2008-09-176412. Epub 2009 Mar 31. Blood. 2009. PMID: 19336761 Free PMC article.

5

Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus.

Beard BC, Keyser KA, Trobridge GD, Peterson LJ, Miller DG, Jacobs M, Kaul R, Kiem HP. Beard BC, et al. Among authors: trobridge gd. Hum Gene Ther. 2007 May;18(5):423-34. doi: 10.1089/hum.2007.011. Hum Gene Ther. 2007. PMID: 17518616

6

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.

Zhang XB, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries RK, Kiem HP. Zhang XB, et al. Among authors: trobridge gd. J Clin Invest. 2008 Apr;118(4):1502-10. doi: 10.1172/JCI34371. J Clin Invest. 2008. PMID: 18357342 Free PMC article.

7

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors.

Trobridge GD, Beard BC, Gooch C, Wohlfahrt M, Olsen P, Fletcher J, Malik P, Kiem HP. Trobridge GD, et al. Blood. 2008 Jun 15;111(12):5537-43. doi: 10.1182/blood-2007-09-115022. Epub 2008 Apr 3. Blood. 2008. PMID: 18388180 Free PMC article.

8

Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency.

Trobridge GD, Allen J, Peterson L, Ironside C, Russell DW, Kiem HP. Trobridge GD, et al. Hum Gene Ther. 2009 May;20(5):519-23. doi: 10.1089/hum.2008.170. Hum Gene Ther. 2009. PMID: 19199822 Free PMC article.

9

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.

Trobridge GD, Wu RA, Beard BC, Chiu SY, Muñoz NM, von Laer D, Rossi JJ, Kiem HP. Trobridge GD, et al. PLoS One. 2009 Nov 2;4(11):e7693. doi: 10.1371/journal.pone.0007693. PLoS One. 2009. PMID: 19888329 Free PMC article.

10

Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors.

Enssle J, Trobridge GD, Keyser KA, Ironside C, Beard BC, Kiem HP. Enssle J, et al. Among authors: trobridge gd. Hum Gene Ther. 2010 Apr;21(4):397-403. doi: 10.1089/hum.2009.076. Hum Gene Ther. 2010. PMID: 19947827 Free PMC article.

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