Morris JC - Search Results

1

A fluorescent assay for ceramide synthase activity.

Kim HJ, Qiao Q, Toop HD, Morris JC, Don AS. Kim HJ, et al. Among authors: morris jc. J Lipid Res. 2012 Aug;53(8):1701-7. doi: 10.1194/jlr.D025627. Epub 2012 Jun 1. J Lipid Res. 2012. PMID: 22661289 Free PMC article.

2

Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate.

Jary E, Bee T, Walker SR, Chung SK, Seo KC, Morris JC, Don AS. Jary E, et al. Among authors: morris jc. Mol Pharmacol. 2010 Oct;78(4):685-92. doi: 10.1124/mol.110.064873. Epub 2010 Jul 7. Mol Pharmacol. 2010. PMID: 20610734

3

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

Collison A, Hatchwell L, Verrills N, Wark PA, de Siqueira AP, Tooze M, Carpenter H, Don AS, Morris JC, Zimmermann N, Bartlett NW, Rothenberg ME, Johnston SL, Foster PS, Mattes J. Collison A, et al. Among authors: morris jc. Nat Med. 2013 Feb;19(2):232-7. doi: 10.1038/nm.3049. Epub 2013 Jan 20. Nat Med. 2013. PMID: 23334847

4

Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.

Hatchwell L, Girkin J, Dun MD, Morten M, Verrills N, Toop HD, Morris JC, Johnston SL, Foster PS, Collison A, Mattes J. Hatchwell L, et al. Among authors: morris jc. J Allergy Clin Immunol. 2014 Jun;133(6):1720-7. doi: 10.1016/j.jaci.2013.11.014. Epub 2014 Jan 2. J Allergy Clin Immunol. 2014. PMID: 24388637

5

Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease.

Collison A, Li J, Pereira de Siqueira A, Zhang J, Toop HD, Morris JC, Foster PS, Mattes J. Collison A, et al. Among authors: morris jc. Am J Respir Cell Mol Biol. 2014 Jul;51(1):86-93. doi: 10.1165/rcmb.2013-0490OC. Am J Respir Cell Mol Biol. 2014. PMID: 24484417

6

MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity.

Li JJ, Tay HL, Maltby S, Xiang Y, Eyers F, Hatchwell L, Zhou H, Toop HD, Morris JC, Nair P, Mattes J, Foster PS, Yang M. Li JJ, et al. Among authors: morris jc. J Allergy Clin Immunol. 2015 Aug;136(2):462-73. doi: 10.1016/j.jaci.2014.11.044. Epub 2015 Mar 13. J Allergy Clin Immunol. 2015. PMID: 25772595

7

Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors.

Toop HD, Don AS, Morris JC. Toop HD, et al. Among authors: morris jc. Org Biomol Chem. 2015 Dec 28;13(48):11593-6. doi: 10.1039/c5ob01931a. Epub 2015 Nov 4. Org Biomol Chem. 2015. PMID: 26535908

8

Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia.

Toop HD, Dun MD, Ross BK, Flanagan HM, Verrills NM, Morris JC. Toop HD, et al. Among authors: morris jc. Org Biomol Chem. 2016 May 18;14(20):4605-16. doi: 10.1039/c6ob00556j. Org Biomol Chem. 2016. PMID: 27102578

9

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

Smith AM, Dun MD, Lee EM, Harrison C, Kahl R, Flanagan H, Panicker N, Mashkani B, Don AS, Morris J, Toop H, Lock RB, Powell JA, Thomas D, Guthridge MA, Moore A, Ashman LK, Skelding KA, Enjeti A, Verrills NM. Smith AM, et al. Oncotarget. 2016 Jul 26;7(30):47465-47478. doi: 10.18632/oncotarget.10167. Oncotarget. 2016. PMID: 27329844 Free PMC article.

10

Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.

Batson J, Toop HD, Redondo C, Babaei-Jadidi R, Chaikuad A, Wearmouth SF, Gibbons B, Allen C, Tallant C, Zhang J, Du C, Hancox JC, Hawtrey T, Da Rocha J, Griffith R, Knapp S, Bates DO, Morris JC. Batson J, et al. Among authors: morris jc. ACS Chem Biol. 2017 Mar 17;12(3):825-832. doi: 10.1021/acschembio.6b01048. Epub 2017 Feb 6. ACS Chem Biol. 2017. PMID: 28135068 Free article.

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