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Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarials.
Copple IM, Mercer AE, Firman J, Donegan G, Herpers B, Wong MH, Chadwick J, Bringela AD, Cristiano ML, van de Water B, Ward SA, O'Neill PM, Park BK. Copple IM, et al. Among authors: firman j. Mol Med. 2012 Sep 25;18(1):1045-55. doi: 10.2119/molmed.2012.00154. Mol Med. 2012. PMID: 22669474 Free PMC article.
Artemisinin-polypyrrole conjugates: synthesis, DNA binding studies and preliminary antiproliferative evaluation.
La Pensée L, Sabbani S, Sharma R, Bhamra I, Shore E, Chadwick AE, Berry NG, Firman J, Araujo NC, Cabral L, Cristiano ML, Bateman C, Janneh O, Gavrila A, Wu YH, Hussain A, Ward SA, Stocks PA, Cosstick R, O'Neill PM. La Pensée L, et al. Among authors: firman j. ChemMedChem. 2013 May;8(5):709-18. doi: 10.1002/cmdc.201200536. Epub 2013 Mar 11. ChemMedChem. 2013. PMID: 23495190
Potential of ToxCast Data in the Safety Assessment of Food Chemicals.
Punt A, Firman J, Boobis A, Cronin M, Gosling JP, Wilks MF, Hepburn PA, Thiel A, Fussell KC. Punt A, et al. Among authors: firman j. Toxicol Sci. 2020 Apr 1;174(2):326-340. doi: 10.1093/toxsci/kfaa008. Toxicol Sci. 2020. PMID: 32040188 Free PMC article.
In vitro Liver Zonation of Primary Rat Hepatocytes.
Tomlinson L, Hyndman L, Firman JW, Bentley R, Kyffin JA, Webb SD, McGinty S, Sharma P. Tomlinson L, et al. Front Bioeng Biotechnol. 2019 Feb 18;7:17. doi: 10.3389/fbioe.2019.00017. eCollection 2019. Front Bioeng Biotechnol. 2019. PMID: 30834246 Free PMC article.
A scheme to evaluate structural alerts to predict toxicity - Assessing confidence by characterising uncertainties.
Cronin MTD, Bauer FJ, Bonnell M, Campos B, Ebbrell DJ, Firman JW, Gutsell S, Hodges G, Patlewicz G, Sapounidou M, Spînu N, Thomas PC, Worth AP. Cronin MTD, et al. Among authors: firman jw. Regul Toxicol Pharmacol. 2022 Nov;135:105249. doi: 10.1016/j.yrtph.2022.105249. Epub 2022 Aug 27. Regul Toxicol Pharmacol. 2022. PMID: 36041585 Free PMC article.
80 results