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Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding.
Smalls-Mantey A, Doria-Rose N, Klein R, Patamawenu A, Migueles SA, Ko SY, Hallahan CW, Wong H, Liu B, You L, Scheid J, Kappes JC, Ochsenbauer C, Nabel GJ, Mascola JR, Connors M. Smalls-Mantey A, et al. Among authors: connors m. J Virol. 2012 Aug;86(16):8672-80. doi: 10.1128/JVI.00287-12. Epub 2012 Jun 6. J Virol. 2012. PMID: 22674985 Free PMC article.
Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.
Connors M, Kulkarni AB, Collins PL, Firestone CY, Holmes KL, Morse HC 3rd, Murphy BR. Connors M, et al. J Virol. 1992 Feb;66(2):1277-81. doi: 10.1128/JVI.66.2.1277-1281.1992. J Virol. 1992. PMID: 1731105 Free PMC article.
Resistance to replication of human immunodeficiency virus challenge in SCID-Hu mice engrafted with peripheral blood mononuclear cells of nonprogressors is mediated by CD8(+) T cells and associated with a proliferative response to p24 antigen.
de Quiros JC, Shupert WL, McNeil AC, Gea-Banacloche JC, Flanigan M, Savage A, Martino L, Weiskopf EE, Imamichi H, Zhang YM, Adelsburger J, Stevens R, Murphy PM, Zimmerman PA, Hallahan CW, Davey RT Jr, Connors M. de Quiros JC, et al. Among authors: connors m. J Virol. 2000 Feb;74(4):2023-8. doi: 10.1128/jvi.74.4.2023-2028.2000. J Virol. 2000. PMID: 10644376 Free PMC article.
HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.
Migueles SA, Sabbaghian MS, Shupert WL, Bettinotti MP, Marincola FM, Martino L, Hallahan CW, Selig SM, Schwartz D, Sullivan J, Connors M. Migueles SA, et al. Among authors: connors m. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2709-14. doi: 10.1073/pnas.050567397. Proc Natl Acad Sci U S A. 2000. PMID: 10694578 Free PMC article.
446 results