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Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions.
Barrera NP, Isaacson SC, Zhou M, Bavro VN, Welch A, Schaedler TA, Seeger MA, Miguel RN, Korkhov VM, van Veen HW, Venter H, Walmsley AR, Tate CG, Robinson CV. Barrera NP, et al. Among authors: seeger ma. Nat Methods. 2009 Aug;6(8):585-7. doi: 10.1038/nmeth.1347. Epub 2009 Jul 5. Nat Methods. 2009. PMID: 19578383 Free PMC article.
A multidrug ABC transporter with a taste for salt.
Velamakanni S, Lau CH, Gutmann DA, Venter H, Barrera NP, Seeger MA, Woebking B, Matak-Vinkovic D, Balakrishnan L, Yao Y, U EC, Shilling RA, Robinson CV, Thorn P, van Veen HW. Velamakanni S, et al. Among authors: seeger ma. PLoS One. 2009 Jul 10;4(7):e6137. doi: 10.1371/journal.pone.0006137. PLoS One. 2009. PMID: 19593434 Free PMC article.
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Eicher T, Cha HJ, Seeger MA, Brandstätter L, El-Delik J, Bohnert JA, Kern WV, Verrey F, Grütter MG, Diederichs K, Pos KM. Eicher T, et al. Among authors: seeger ma. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5687-92. doi: 10.1073/pnas.1114944109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451937 Free PMC article.
114 results