Laraia L - Search Results

1

Palladium-catalysed cross-coupling of vinyldisiloxanes with benzylic and allylic halides and sulfonates.

Frye EC, O'Connor CJ, Twigg DG, Elbert B, Laraia L, Hulcoop DG, Venkitaraman AR, Spring DR. Frye EC, et al. Among authors: laraia l. Chemistry. 2012 Jul 9;18(28):8774-9. doi: 10.1002/chem.201200431. Epub 2012 Jun 8. Chemistry. 2012. PMID: 22678946

2

A concise total synthesis of deoxyschizandrin and exploration of its antiproliferative effects and those of structurally related derivatives.

Zheng S, Aves SJ, Laraia L, Galloway WR, Pike KG, Wu W, Spring DR. Zheng S, et al. Among authors: laraia l. Chemistry. 2012 Mar 12;18(11):3193-8. doi: 10.1002/chem.201103530. Epub 2012 Feb 3. Chemistry. 2012. PMID: 22307955

3

Vinyldisiloxanes: their synthesis, cross coupling and applications.

Sore HF, Boehner CM, Laraia L, Logoteta P, Prestinari C, Scott M, Williams K, Galloway WR, Spring DR. Sore HF, et al. Among authors: laraia l. Org Biomol Chem. 2011 Jan 21;9(2):504-15. doi: 10.1039/c0ob00338g. Epub 2010 Oct 12. Org Biomol Chem. 2011. PMID: 20941422

4

Chemical genetics.

O'Connor CJ, Laraia L, Spring DR. O'Connor CJ, et al. Among authors: laraia l. Chem Soc Rev. 2011 Aug;40(8):4332-45. doi: 10.1039/c1cs15053g. Epub 2011 May 12. Chem Soc Rev. 2011. PMID: 21562678 Review.

5

A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.

O'Connell KM, Beckmann HS, Laraia L, Horsley HT, Bender A, Venkitaraman AR, Spring DR. O'Connell KM, et al. Among authors: laraia l. Org Biomol Chem. 2012 Oct 7;10(37):7545-51. doi: 10.1039/c2ob26272j. Org Biomol Chem. 2012. PMID: 22890306

6

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.

Laraia L, McKenzie G, Spring DR, Venkitaraman AR, Huggins DJ. Laraia L, et al. Chem Biol. 2015 Jun 18;22(6):689-703. doi: 10.1016/j.chembiol.2015.04.019. Chem Biol. 2015. PMID: 26091166 Free PMC article. Review.

7

Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck-Suzuki reaction.

Alza E, Laraia L, Ibbeson BM, Collins S, Galloway WRJD, Stokes JE, Venkitaraman AR, Spring DR. Alza E, et al. Among authors: laraia l. Chem Sci. 2015 Jan 1;6(1):390-396. doi: 10.1039/c4sc02547d. Epub 2014 Sep 9. Chem Sci. 2015. PMID: 28966765 Free PMC article.

8

Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity.

Zheng S, Laraia L, O' Connor CJ, Sorrell D, Tan YS, Xu Z, Venkitaraman AR, Wu W, Spring DR. Zheng S, et al. Among authors: laraia l. Org Biomol Chem. 2012 Apr 7;10(13):2590-3. doi: 10.1039/c2ob25065a. Epub 2012 Feb 23. Org Biomol Chem. 2012. PMID: 22361895

9

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis.

Ibbeson BM, Laraia L, Alza E, O' Connor CJ, Tan YS, Davies HM, McKenzie G, Venkitaraman AR, Spring DR. Ibbeson BM, et al. Among authors: laraia l. Nat Commun. 2014;5:3155. doi: 10.1038/ncomms4155. Nat Commun. 2014. PMID: 24434687 Free article.

10

High content screening of diverse compound libraries identifies potent modulators of tubulin dynamics.

Laraia L, Stokes J, Emery A, McKenzie GJ, Venkitaraman AR, Spring DR. Laraia L, et al. ACS Med Chem Lett. 2014 Feb 24;5(5):598-603. doi: 10.1021/ml5000564. eCollection 2014 May 8. ACS Med Chem Lett. 2014. PMID: 24900887 Free PMC article.

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