Venkitaraman AR - Search Results

1

Palladium-catalysed cross-coupling of vinyldisiloxanes with benzylic and allylic halides and sulfonates.

Frye EC, O'Connor CJ, Twigg DG, Elbert B, Laraia L, Hulcoop DG, Venkitaraman AR, Spring DR. Frye EC, et al. Among authors: venkitaraman ar. Chemistry. 2012 Jul 9;18(28):8774-9. doi: 10.1002/chem.201200431. Epub 2012 Jun 8. Chemistry. 2012. PMID: 22678946

2

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.

Laraia L, McKenzie G, Spring DR, Venkitaraman AR, Huggins DJ. Laraia L, et al. Among authors: venkitaraman ar. Chem Biol. 2015 Jun 18;22(6):689-703. doi: 10.1016/j.chembiol.2015.04.019. Chem Biol. 2015. PMID: 26091166 Free PMC article. Review.

3

A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.

O'Connell KM, Beckmann HS, Laraia L, Horsley HT, Bender A, Venkitaraman AR, Spring DR. O'Connell KM, et al. Among authors: venkitaraman ar. Org Biomol Chem. 2012 Oct 7;10(37):7545-51. doi: 10.1039/c2ob26272j. Org Biomol Chem. 2012. PMID: 22890306

4

High content screening of diverse compound libraries identifies potent modulators of tubulin dynamics.

Laraia L, Stokes J, Emery A, McKenzie GJ, Venkitaraman AR, Spring DR. Laraia L, et al. Among authors: venkitaraman ar. ACS Med Chem Lett. 2014 Feb 24;5(5):598-603. doi: 10.1021/ml5000564. eCollection 2014 May 8. ACS Med Chem Lett. 2014. PMID: 24900887 Free PMC article.

5

Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck-Suzuki reaction.

Alza E, Laraia L, Ibbeson BM, Collins S, Galloway WRJD, Stokes JE, Venkitaraman AR, Spring DR. Alza E, et al. Among authors: venkitaraman ar. Chem Sci. 2015 Jan 1;6(1):390-396. doi: 10.1039/c4sc02547d. Epub 2014 Sep 9. Chem Sci. 2015. PMID: 28966765 Free PMC article.

6

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis.

Ibbeson BM, Laraia L, Alza E, O' Connor CJ, Tan YS, Davies HM, McKenzie G, Venkitaraman AR, Spring DR. Ibbeson BM, et al. Among authors: venkitaraman ar. Nat Commun. 2014;5:3155. doi: 10.1038/ncomms4155. Nat Commun. 2014. PMID: 24434687 Free article.

7

Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity.

Zheng S, Laraia L, O' Connor CJ, Sorrell D, Tan YS, Xu Z, Venkitaraman AR, Wu W, Spring DR. Zheng S, et al. Among authors: venkitaraman ar. Org Biomol Chem. 2012 Apr 7;10(13):2590-3. doi: 10.1039/c2ob25065a. Epub 2012 Feb 23. Org Biomol Chem. 2012. PMID: 22361895

8

Linear aliphatic dialkynes as alternative linkers for double-click stapling of p53-derived peptides.

Lau YH, de Andrade P, McKenzie GJ, Venkitaraman AR, Spring DR. Lau YH, et al. Among authors: venkitaraman ar. Chembiochem. 2014 Dec 15;15(18):2680-3. doi: 10.1002/cbic.201402374. Epub 2014 Oct 29. Chembiochem. 2014. PMID: 25354189

9

Rational methods for the selection of diverse screening compounds.

Huggins DJ, Venkitaraman AR, Spring DR. Huggins DJ, et al. Among authors: venkitaraman ar. ACS Chem Biol. 2011 Mar 18;6(3):208-17. doi: 10.1021/cb100420r. Epub 2011 Feb 15. ACS Chem Biol. 2011. PMID: 21261294 Free PMC article. Review.

10

Investigating peptide sequence variations for 'double-click' stapled p53 peptides.

Lau YH, de Andrade P, Sköld N, McKenzie GJ, Venkitaraman AR, Verma C, Lane DP, Spring DR. Lau YH, et al. Among authors: venkitaraman ar. Org Biomol Chem. 2014 Jun 28;12(24):4074-7. doi: 10.1039/c4ob00742e. Org Biomol Chem. 2014. PMID: 24817343

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