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Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.
Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I. Naito AT, et al. Among authors: zhu w. Cell. 2012 Jun 8;149(6):1298-313. doi: 10.1016/j.cell.2012.03.047. Cell. 2012. PMID: 22682250 Free PMC article.
Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart.
Toko H, Zhu W, Takimoto E, Shiojima I, Hiroi Y, Zou Y, Oka T, Akazawa H, Mizukami M, Sakamoto M, Terasaki F, Kitaura Y, Takano H, Nagai T, Nagai R, Komuro I. Toko H, et al. Among authors: zhu w. J Biol Chem. 2002 Jul 5;277(27):24735-43. doi: 10.1074/jbc.M107669200. Epub 2002 Mar 11. J Biol Chem. 2002. PMID: 11889119 Free article.
G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes.
Harada M, Qin Y, Takano H, Minamino T, Zou Y, Toko H, Ohtsuka M, Matsuura K, Sano M, Nishi J, Iwanaga K, Akazawa H, Kunieda T, Zhu W, Hasegawa H, Kunisada K, Nagai T, Nakaya H, Yamauchi-Takihara K, Komuro I. Harada M, et al. Among authors: zhu w. Nat Med. 2005 Mar;11(3):305-11. doi: 10.1038/nm1199. Epub 2005 Feb 20. Nat Med. 2005. PMID: 15723072
Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes.
Monzen K, Zhu W, Kasai H, Hiroi Y, Hosoda T, Akazawa H, Zou Y, Hayashi D, Yamazaki T, Nagai R, Komuro I. Monzen K, et al. Among authors: zhu w. Biochem Biophys Res Commun. 2002 Nov 8;298(4):493-500. doi: 10.1016/s0006-291x(02)02497-x. Biochem Biophys Res Commun. 2002. PMID: 12408979
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