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Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Jadhav RD, Kadam KS, Kandre S, Guha T, Reddy MM, Brahma MK, Deshmukh NJ, Dixit A, Doshi L, Potdar N, Enose AA, Vishwakarma RA, Sivaramakrishnan H, Srinivasan S, Nemmani KV, Gupte A, Gangopadhyay AK, Sharma R. Jadhav RD, et al. Among authors: dixit a. Eur J Med Chem. 2012 Aug;54:324-42. doi: 10.1016/j.ejmech.2012.05.016. Epub 2012 May 22. Eur J Med Chem. 2012. PMID: 22683241
Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Motiwala H, Kandre S, Birar V, Kadam KS, Rodge A, Jadhav RD, Mahesh Kumar Reddy M, Brahma MK, Deshmukh NJ, Dixit A, Doshi L, Gupte A, Gangopadhyay AK, Vishwakarma RA, Srinivasan S, Sharma M, Nemmani KV, Sharma R. Motiwala H, et al. Among authors: dixit a. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5812-7. doi: 10.1016/j.bmcl.2011.07.109. Epub 2011 Aug 4. Bioorg Med Chem Lett. 2011. PMID: 21868220
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits.
B-Rao C, Kulkarni-Almeida A, Katkar KV, Khanna S, Ghosh U, Keche A, Shah P, Srivastava A, Korde V, Nemmani KV, Deshmukh NJ, Dixit A, Brahma MK, Bahirat U, Doshi L, Sharma R, Sivaramakrishnan H. B-Rao C, et al. Among authors: dixit a. Bioorg Med Chem. 2012 May 1;20(9):2930-9. doi: 10.1016/j.bmc.2012.03.019. Epub 2012 Mar 14. Bioorg Med Chem. 2012. PMID: 22483591
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
Khanna S, Burudkar S, Bajaj K, Shah P, Keche A, Ghosh U, Desai A, Srivastava A, Kulkarni-Almeida A, Deshmukh NJ, Dixit A, Brahma MK, Bahirat U, Doshi L, Nemmani KV, Tannu P, Damre A, B-Rao C, Sharma R, Sivaramakrishnan H. Khanna S, et al. Among authors: dixit a. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7543-6. doi: 10.1016/j.bmcl.2012.10.029. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23122864
Lead optimization of isocytosine-derived xanthine oxidase inhibitors.
Bajaj K, Burudkar S, Shah P, Keche A, Ghosh U, Tannu P, Khanna S, Srivastava A, Deshmukh NJ, Dixit A, Ahire Y, Damre A, Nemmani KV, Kulkarni-Almeida A, B-Rao C, Sharma R, Sivaramakrishnan H. Bajaj K, et al. Among authors: dixit a. Bioorg Med Chem Lett. 2013 Feb 1;23(3):834-8. doi: 10.1016/j.bmcl.2012.11.057. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23265878
18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.
Anandharajan R, Sayyed SG, Doshi LS, Dixit P, Chandak PG, Dixit AV, Brahma MK, Deshmukh NJ, Gupte R, Damre A, Suthar J, Padigaru M, Sharma SD, Nemmani KV. Anandharajan R, et al. Among authors: dixit av, dixit p. Metabolism. 2009 Oct;58(10):1503-16. doi: 10.1016/j.metabol.2009.04.036. Epub 2009 Jul 15. Metabolism. 2009. PMID: 19608207 Free article.
1,110 results