D'Hooge R - Search Results

1

Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice.

Kowalewski B, Lamanna WC, Lawrence R, Damme M, Stroobants S, Padva M, Kalus I, Frese MA, Lübke T, Lüllmann-Rauch R, D'Hooge R, Esko JD, Dierks T. Kowalewski B, et al. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10310-5. doi: 10.1073/pnas.1202071109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689975 Free PMC article.

2

Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.

Kalus I, Salmen B, Viebahn C, von Figura K, Schmitz D, D'Hooge R, Dierks T. Kalus I, et al. J Cell Mol Med. 2009 Nov-Dec;13(11-12):4505-21. doi: 10.1111/j.1582-4934.2008.00558.x. J Cell Mol Med. 2009. PMID: 20394677 Free PMC article.

3

A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease.

Wolf H, Damme M, Stroobants S, D'Hooge R, Beck HC, Hermans-Borgmeyer I, Lüllmann-Rauch R, Dierks T, Lübke T. Wolf H, et al. Dis Model Mech. 2016 Sep 1;9(9):1015-28. doi: 10.1242/dmm.025122. Epub 2016 Aug 4. Dis Model Mech. 2016. PMID: 27491075 Free PMC article.

4

Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice.

Stroobants S, Wolf H, Callaerts-Vegh Z, Dierks T, Lübke T, D'Hooge R. Stroobants S, et al. Front Behav Neurosci. 2018 Apr 12;12:69. doi: 10.3389/fnbeh.2018.00069. eCollection 2018. Front Behav Neurosci. 2018. PMID: 29706874 Free PMC article.

5

Aged Tmem106b knockout mice display gait deficits in coincidence with Purkinje cell loss and only limited signs of non-motor dysfunction.

Stroobants S, D'Hooge R, Damme M. Stroobants S, et al. Brain Pathol. 2021 Mar;31(2):223-238. doi: 10.1111/bpa.12903. Epub 2020 Nov 1. Brain Pathol. 2021. PMID: 33016371 Free PMC article.

6

Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in α-mannosidosis.

Damme M, Stroobants S, Walkley SU, Lüllmann-Rauch R, D'Hooge R, Fogh J, Saftig P, Lübke T, Blanz J. Damme M, et al. J Neuropathol Exp Neurol. 2011 Jan;70(1):83-94. doi: 10.1097/NEN.0b013e31820428fa. J Neuropathol Exp Neurol. 2011. PMID: 21157375 Free PMC article.

7

Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis mice.

Damme M, Stroobants S, Lüdemann M, Rothaug M, Lüllmann-Rauch R, Beck HC, Ericsson A, Andersson C, Fogh J, D'Hooge R, Saftig P, Blanz J. Damme M, et al. Ann Clin Transl Neurol. 2015 Sep 19;2(11):987-1001. doi: 10.1002/acn3.245. eCollection 2015 Nov. Ann Clin Transl Neurol. 2015. PMID: 26817023 Free PMC article.

8

Phenotype of arylsulfatase A-deficient mice: relationship to human metachromatic leukodystrophy.

Hess B, Saftig P, Hartmann D, Coenen R, Lüllmann-Rauch R, Goebel HH, Evers M, von Figura K, D'Hooge R, Nagels G, De Deyn P, Peters C, Gieselmann V. Hess B, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14821-6. doi: 10.1073/pnas.93.25.14821. Proc Natl Acad Sci U S A. 1996. PMID: 8962139 Free PMC article.

9

Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1.

Kollmann K, Damme M, Deuschl F, Kahle J, D'Hooge R, Lüllmann-Rauch R, Lübke T. Kollmann K, et al. FEBS J. 2009 Mar;276(5):1356-69. doi: 10.1111/j.1742-4658.2009.06877.x. FEBS J. 2009. PMID: 19187242 Free article.

10

Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice.

Stroobants S, Damme M, Van der Jeugd A, Vermaercke B, Andersson C, Fogh J, Saftig P, Blanz J, D'Hooge R. Stroobants S, et al. Neurobiol Dis. 2017 Oct;106:255-268. doi: 10.1016/j.nbd.2017.07.013. Epub 2017 Jul 15. Neurobiol Dis. 2017. PMID: 28720484

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