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Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages.
Sakai K, Nagashima S, Wakabayashi T, Tumenbayar B, Hayakawa H, Hayakawa M, Karasawa T, Ohashi K, Yamazaki H, Takei A, Takei S, Yamamuro D, Takahashi M, Yagyu H, Osuga JI, Takahashi M, Tominaga SI, Ishibashi S. Sakai K, et al. Among authors: ohashi k. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2590-2600. doi: 10.1161/ATVBAHA.118.311664. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354246
p53 involvement in the pathogenesis of fatty liver disease.
Yahagi N, Shimano H, Matsuzaka T, Sekiya M, Najima Y, Okazaki S, Okazaki H, Tamura Y, Iizuka Y, Inoue N, Nakagawa Y, Takeuchi Y, Ohashi K, Harada K, Gotoda T, Nagai R, Kadowaki T, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: ohashi k. J Biol Chem. 2004 May 14;279(20):20571-5. doi: 10.1074/jbc.M400884200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985341 Free article.
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.
Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H. Takeuchi Y, et al. Among authors: ohashi k. J Biol Chem. 2010 Apr 9;285(15):11681-91. doi: 10.1074/jbc.M109.096107. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145241 Free PMC article.
p53 Activation in adipocytes of obese mice.
Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Gotoda T, Nagai R, Kimura S, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: ohashi k. J Biol Chem. 2003 Jul 11;278(28):25395-400. doi: 10.1074/jbc.M302364200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734185 Free article.
Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice.
Matsuzaka T, Shimano H, Yahagi N, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Tomita S, Sekiya M, Hasty A, Nakagawa Y, Sone H, Toyoshima H, Ishibashi S, Osuga J, Yamada N. Matsuzaka T, et al. Among authors: ohashi k. Diabetes. 2004 Mar;53(3):560-9. doi: 10.2337/diabetes.53.3.560. Diabetes. 2004. PMID: 14988238
SREBP-1-independent regulation of lipogenic gene expression in adipocytes.
Sekiya M, Yahagi N, Matsuzaka T, Takeuchi Y, Nakagawa Y, Takahashi H, Okazaki H, Iizuka Y, Ohashi K, Gotoda T, Ishibashi S, Nagai R, Yamazaki T, Kadowaki T, Yamada N, Osuga J, Shimano H. Sekiya M, et al. Among authors: ohashi k. J Lipid Res. 2007 Jul;48(7):1581-91. doi: 10.1194/jlr.M700033-JLR200. Epub 2007 Apr 24. J Lipid Res. 2007. PMID: 17456898 Free article.
In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.
Takeuchi Y, Yahagi N, Nakagawa Y, Matsuzaka T, Shimizu R, Sekiya M, Iizuka Y, Ohashi K, Gotoda T, Yamamoto M, Nagai R, Kadowaki T, Yamada N, Osuga J, Shimano H. Takeuchi Y, et al. Among authors: ohashi k. Biochem Biophys Res Commun. 2007 Nov 16;363(2):329-35. doi: 10.1016/j.bbrc.2007.08.165. Epub 2007 Sep 6. Biochem Biophys Res Commun. 2007. PMID: 17880923 Free article.
Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy.
Osaki Y, Nakagawa Y, Miyahara S, Iwasaki H, Ishii A, Matsuzaka T, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Suzuki H, Sone H, Ohashi K, Ishibashi S, Yamada N, Shimano H. Osaki Y, et al. Among authors: ohashi k. Biochem Biophys Res Commun. 2015 Oct 23;466(3):536-40. doi: 10.1016/j.bbrc.2015.09.065. Epub 2015 Sep 14. Biochem Biophys Res Commun. 2015. PMID: 26381177
2,655 results