Chen-Kiang S - Search Results

1

Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4.

Huang X, Di Liberto M, Jayabalan D, Liang J, Ely S, Bretz J, Shaffer AL 3rd, Louie T, Chen I, Randolph S, Hahn WC, Staudt LM, Niesvizky R, Moore MA, Chen-Kiang S. Huang X, et al. Blood. 2012 Aug 2;120(5):1095-106. doi: 10.1182/blood-2012-03-415984. Epub 2012 Jun 20. Blood. 2012. PMID: 22718837 Free PMC article.

2

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma.

Leonard JP, LaCasce AS, Smith MR, Noy A, Chirieac LR, Rodig SJ, Yu JQ, Vallabhajosula S, Schoder H, English P, Neuberg DS, Martin P, Millenson MM, Ely SA, Courtney R, Shaik N, Wilner KD, Randolph S, Van den Abbeele AD, Chen-Kiang SY, Yap JT, Shapiro GI. Leonard JP, et al. Blood. 2012 May 17;119(20):4597-607. doi: 10.1182/blood-2011-10-388298. Epub 2012 Mar 1. Blood. 2012. PMID: 22383795 Free article. Clinical Trial.

3

The cancer-testis antigens CT7 (MAGE-C1) and MAGE-A3/6 are commonly expressed in multiple myeloma and correlate with plasma-cell proliferation.

Jungbluth AA, Ely S, DiLiberto M, Niesvizky R, Williamson B, Frosina D, Chen YT, Bhardwaj N, Chen-Kiang S, Old LJ, Cho HJ. Jungbluth AA, et al. Blood. 2005 Jul 1;106(1):167-74. doi: 10.1182/blood-2004-12-4931. Epub 2005 Mar 10. Blood. 2005. PMID: 15761016 Free article.

4

Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma.

Ely S, Di Liberto M, Niesvizky R, Baughn LB, Cho HJ, Hatada EN, Knowles DM, Lane J, Chen-Kiang S. Ely S, et al. Cancer Res. 2005 Dec 15;65(24):11345-53. doi: 10.1158/0008-5472.CAN-05-2159. Cancer Res. 2005. PMID: 16357141

5

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6.

Baughn LB, Di Liberto M, Wu K, Toogood PL, Louie T, Gottschalk R, Niesvizky R, Cho H, Ely S, Moore MA, Chen-Kiang S. Baughn LB, et al. Cancer Res. 2006 Aug 1;66(15):7661-7. doi: 10.1158/0008-5472.CAN-06-1098. Cancer Res. 2006. PMID: 16885367

6

Noxa mediates p18INK4c cell-cycle control of homeostasis in B cells and plasma cell precursors.

Bretz J, Garcia J, Huang X, Kang L, Zhang Y, Toellner KM, Chen-Kiang S. Bretz J, et al. Blood. 2011 Feb 17;117(7):2179-88. doi: 10.1182/blood-2010-06-288027. Epub 2010 Dec 16. Blood. 2011. PMID: 21163929 Free PMC article.

7

Induction of prolonged early G1 arrest by CDK4/CDK6 inhibition reprograms lymphoma cells for durable PI3Kδ inhibition through PIK3IP1.

Chiron D, Martin P, Di Liberto M, Huang X, Ely S, Lannutti BJ, Leonard JP, Mason CE, Chen-Kiang S. Chiron D, et al. Cell Cycle. 2013 Jun 15;12(12):1892-900. doi: 10.4161/cc.24928. Epub 2013 May 15. Cell Cycle. 2013. PMID: 23676220 Free PMC article.

8

CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.

Yang C, Boyson CA, Di Liberto M, Huang X, Hannah J, Dorn DC, Moore MA, Chen-Kiang S, Zhou P. Yang C, et al. Cancer Res. 2015 May 1;75(9):1838-45. doi: 10.1158/0008-5472.CAN-14-2486. Epub 2015 Mar 5. Cancer Res. 2015. PMID: 25744718 Free PMC article.

9

Cell Cycle Dysregulation in Mantle Cell Lymphoma: Genomics and Therapy.

Wang K, Huang X, Di Liberto M, Chen-Kiang S. Wang K, et al. Among authors: chen kiang s. Hematol Oncol Clin North Am. 2020 Oct;34(5):809-823. doi: 10.1016/j.hoc.2020.05.003. Epub 2020 Aug 1. Hematol Oncol Clin North Am. 2020. PMID: 32861279 Free PMC article. Review.

10

Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.

Wang ES, Wu K, Chin AC, Chen-Kiang S, Pongracz K, Gryaznov S, Moore MA. Wang ES, et al. Blood. 2004 Jan 1;103(1):258-66. doi: 10.1182/blood-2003-02-0546. Epub 2003 Sep 11. Blood. 2004. PMID: 12969977 Free article.

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