Deak M - Search Results

1

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM. Kondapalli C, et al. Among authors: deak m. Open Biol. 2012 May;2(5):120080. doi: 10.1098/rsob.120080. Open Biol. 2012. PMID: 22724072 Free PMC article.

2

Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.

Woodroof HI, Pogson JH, Begley M, Cantley LC, Deak M, Campbell DG, van Aalten DM, Whitworth AJ, Alessi DR, Muqit MM. Woodroof HI, et al. Among authors: deak m. Open Biol. 2011 Nov;1(3):110012. doi: 10.1098/rsob.110012. Open Biol. 2011. PMID: 22645651 Free PMC article.

3

Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

Kimber WA, Deak M, Prescott AR, Alessi DR. Kimber WA, et al. Among authors: deak m. Biochem J. 2003 Dec 1;376(Pt 2):525-35. doi: 10.1042/BJ20031154. Biochem J. 2003. PMID: 14516276 Free PMC article.

4

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.

Vitari AC, Deak M, Morrice NA, Alessi DR. Vitari AC, et al. Among authors: deak m. Biochem J. 2005 Oct 1;391(Pt 1):17-24. doi: 10.1042/BJ20051180. Biochem J. 2005. PMID: 16083423 Free PMC article.

5

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

Al-Hakim AK, Göransson O, Deak M, Toth R, Campbell DG, Morrice NA, Prescott AR, Alessi DR. Al-Hakim AK, et al. Among authors: deak m. J Cell Sci. 2005 Dec 1;118(Pt 23):5661-73. doi: 10.1242/jcs.02670. J Cell Sci. 2005. PMID: 16306228

6

The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation.

Jaleel M, Villa F, Deak M, Toth R, Prescott AR, Van Aalten DM, Alessi DR. Jaleel M, et al. Among authors: deak m. Biochem J. 2006 Mar 15;394(Pt 3):545-55. doi: 10.1042/BJ20051844. Biochem J. 2006. PMID: 16396636 Free PMC article.

7

Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress.

Zagórska A, Pozo-Guisado E, Boudeau J, Vitari AC, Rafiqi FH, Thastrup J, Deak M, Campbell DG, Morrice NA, Prescott AR, Alessi DR. Zagórska A, et al. Among authors: deak m. J Cell Biol. 2007 Jan 1;176(1):89-100. doi: 10.1083/jcb.200605093. Epub 2006 Dec 26. J Cell Biol. 2007. PMID: 17190791 Free PMC article.

8

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity.

Jaleel M, Nichols RJ, Deak M, Campbell DG, Gillardon F, Knebel A, Alessi DR. Jaleel M, et al. Among authors: deak m. Biochem J. 2007 Jul 15;405(2):307-17. doi: 10.1042/BJ20070209. Biochem J. 2007. PMID: 17447891 Free PMC article.

9

New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion.

Zagórska A, Deak M, Campbell DG, Banerjee S, Hirano M, Aizawa S, Prescott AR, Alessi DR. Zagórska A, et al. Among authors: deak m. Sci Signal. 2010 Mar 30;3(115):ra25. doi: 10.1126/scisignal.2000616. Sci Signal. 2010. PMID: 20354225

10

Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.

Richardson C, Sakamoto K, de los Heros P, Deak M, Campbell DG, Prescott AR, Alessi DR. Richardson C, et al. Among authors: deak m. J Cell Sci. 2011 Mar 1;124(Pt 5):789-800. doi: 10.1242/jcs.077230. J Cell Sci. 2011. PMID: 21321328 Free PMC article.

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