Roebroek AJ - Search Results

1

Loss of endothelial furin leads to cardiac malformation and early postnatal death.

Kim W, Essalmani R, Szumska D, Creemers JW, Roebroek AJ, D'Orleans-Juste P, Bhattacharya S, Seidah NG, Prat A. Kim W, et al. Among authors: roebroek aj. Mol Cell Biol. 2012 Sep;32(17):3382-91. doi: 10.1128/MCB.06331-11. Epub 2012 Jun 25. Mol Cell Biol. 2012. PMID: 22733989 Free PMC article.

2

Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2.

De Bie I, Savaria D, Roebroek AJ, Day R, Lazure C, Van de Ven WJ, Seidah NG. De Bie I, et al. Among authors: roebroek aj. J Biol Chem. 1995 Jan 20;270(3):1020-8. doi: 10.1074/jbc.270.3.1020. J Biol Chem. 1995. PMID: 7836354 Free article.

3

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.

Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N, Roebroek A, Belkaid Y, Creemers J, O'Shea JJ. Pesu M, et al. Nature. 2008 Sep 11;455(7210):246-50. doi: 10.1038/nature07210. Nature. 2008. PMID: 18701887 Free PMC article.

4

Limited redundancy of the proprotein convertase furin in mouse liver.

Roebroek AJ, Taylor NA, Louagie E, Pauli I, Smeijers L, Snellinx A, Lauwers A, Van de Ven WJ, Hartmann D, Creemers JW. Roebroek AJ, et al. J Biol Chem. 2004 Dec 17;279(51):53442-50. doi: 10.1074/jbc.M407152200. Epub 2004 Oct 7. J Biol Chem. 2004. PMID: 15471862 Free article.

5

Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.

Louagie E, Taylor NA, Flamez D, Roebroek AJ, Bright NA, Meulemans S, Quintens R, Herrera PL, Schuit F, Van de Ven WJ, Creemers JW. Louagie E, et al. Among authors: roebroek aj. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12319-24. doi: 10.1073/pnas.0800340105. Epub 2008 Aug 19. Proc Natl Acad Sci U S A. 2008. PMID: 18713856 Free PMC article.

6

Furin-mediated proprotein processing activity: involvement of negatively charged amino acid residues in the substrate binding region.

Roebroek AJ, Creemers JW, Ayoubi TA, Van de Ven WJ. Roebroek AJ, et al. Biochimie. 1994;76(3-4):210-6. doi: 10.1016/0300-9084(94)90148-1. Biochimie. 1994. PMID: 7819325 Review.

7

Furin: the prototype mammalian subtilisin-like proprotein-processing enzyme. Endoproteolytic cleavage at paired basic residues of proproteins of the eukaryotic secretory pathway.

Van de Ven WJ, Creemers JW, Roebroek AJ. Van de Ven WJ, et al. Among authors: roebroek aj. Enzyme. 1991;45(5-6):257-70. doi: 10.1159/000468900. Enzyme. 1991. PMID: 1843280

8

Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis.

Creemers JW, Siezen RJ, Roebroek AJ, Ayoubi TA, Huylebroeck D, Van de Ven WJ. Creemers JW, et al. Among authors: roebroek aj. J Biol Chem. 1993 Oct 15;268(29):21826-34. J Biol Chem. 1993. PMID: 8408037 Free article.

9

Generation of structural and functional diversity in furin-like proteins in Drosophila melanogaster by alternative splicing of the Dfur1 gene.

Roebroek AJ, Creemers JW, Pauli IG, Bogaert T, Van de Ven WJ. Roebroek AJ, et al. EMBO J. 1993 May;12(5):1853-70. doi: 10.1002/j.1460-2075.1993.tb05834.x. EMBO J. 1993. PMID: 8491178 Free PMC article.

10

Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3. Cloning and primary sequence of a 5 kb cDNA.

Creemers JW, Roebroek AJ, Van de Ven WJ. Creemers JW, et al. Among authors: roebroek aj. FEBS Lett. 1992 Mar 23;300(1):82-8. doi: 10.1016/0014-5793(92)80169-h. FEBS Lett. 1992. PMID: 1547893 Free article.

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