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Page 1
Loss of endothelial furin leads to cardiac malformation and early postnatal death.
Kim W, Essalmani R, Szumska D, Creemers JW, Roebroek AJ, D'Orleans-Juste P, Bhattacharya S, Seidah NG, Prat A. Kim W, et al. Among authors: szumska d, d orleans juste p. Mol Cell Biol. 2012 Sep;32(17):3382-91. doi: 10.1128/MCB.06331-11. Epub 2012 Jun 25. Mol Cell Biol. 2012. PMID: 22733989 Free PMC article.
Tagged mutagenesis by efficient Minos-based germ line transposition.
de Wit T, Dekker S, Maas A, Breedveld G, Knoch TA, Langeveld A, Szumska D, Craig R, Bhattacharya S, Grosveld F, Drabek D. de Wit T, et al. Among authors: szumska d. Mol Cell Biol. 2010 Jan;30(1):68-77. doi: 10.1128/MCB.00913-09. Mol Cell Biol. 2010. PMID: 19884347 Free PMC article.
VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.
Szumska D, Pieles G, Essalmani R, Bilski M, Mesnard D, Kaur K, Franklyn A, El Omari K, Jefferis J, Bentham J, Taylor JM, Schneider JE, Arnold SJ, Johnson P, Tymowska-Lalanne Z, Stammers D, Clarke K, Neubauer S, Morris A, Brown SD, Shaw-Smith C, Cama A, Capra V, Ragoussis J, Constam D, Seidah NG, Prat A, Bhattacharya S. Szumska D, et al. Genes Dev. 2008 Jun 1;22(11):1465-77. doi: 10.1101/gad.479408. Genes Dev. 2008. PMID: 18519639 Free PMC article.
Nprl3 is required for normal development of the cardiovascular system.
Kowalczyk MS, Hughes JR, Babbs C, Sanchez-Pulido L, Szumska D, Sharpe JA, Sloane-Stanley JA, Morriss-Kay GM, Smoot LB, Roberts AE, Watkins H, Bhattacharya S, Gibbons RJ, Ponting CP, Wood WG, Higgs DR. Kowalczyk MS, et al. Among authors: szumska d. Mamm Genome. 2012 Aug;23(7-8):404-15. doi: 10.1007/s00335-012-9398-y. Epub 2012 Apr 27. Mamm Genome. 2012. PMID: 22538705
Glucocorticoid receptor is required for foetal heart maturation.
Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE. Rog-Zielinska EA, et al. Among authors: szumska d. Hum Mol Genet. 2013 Aug 15;22(16):3269-82. doi: 10.1093/hmg/ddt182. Epub 2013 Apr 16. Hum Mol Genet. 2013. PMID: 23595884
Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.
Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG. Bard-Chapeau EA, et al. Among authors: szumska d. PLoS One. 2014 Feb 27;9(2):e89397. doi: 10.1371/journal.pone.0089397. eCollection 2014. PLoS One. 2014. PMID: 24586749 Free PMC article.
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