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TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.
Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, He L, Cominelli F, Di Martino L, Djuric Z, Milne GL, Chance M, Sanabria J, Dealwis C, Mikkola D, Naidoo J, Wei S, Tai HH, Gerson SL, Ready JM, Posner B, Willson JK, Markowitz SD. Zhang Y, et al. Among authors: wald d. Science. 2015 Jun 12;348(6240):aaa2340. doi: 10.1126/science.aaa2340. Science. 2015. PMID: 26068857 Free PMC article.
Epigenetic Loss of MLH1 Expression in Normal Human Hematopoietic Stem Cell Clones is Defined by the Promoter CpG Methylation Pattern Observed by High-Throughput Methylation Specific Sequencing.
Kenyon J, Nickel-Meester G, Qing Y, Santos-Guasch G, Drake E, PingfuFu, Sun S, Bai X, Wald D, Arts E, Gerson SL. Kenyon J, et al. Among authors: wald d. Int J Stem Cell Res Ther. 2016;3(2):031. doi: 10.23937/2469-570x/1410031. Epub 2016 May 24. Int J Stem Cell Res Ther. 2016. PMID: 27570841 Free PMC article.
A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support.
Desai A, Zhang Y, Park Y, Dawson DM, Larusch GA, Kasturi L, Wald D, Ready JM, Gerson SL, Markowitz SD. Desai A, et al. Among authors: wald d. Haematologica. 2018 Jun;103(6):1054-1064. doi: 10.3324/haematol.2017.178376. Epub 2018 Feb 22. Haematologica. 2018. PMID: 29472361 Free PMC article.
Loss of GSK3β in hematopoietic stem cells results in normal hematopoiesis in mice.
Lee G, Franklin J, Gupta K, Liu R, Zhou L, Ryder C, Sobieraj L, Molitor L, Abiona O, Meyerson H, Das I, Jackson Z, Wald DN. Lee G, et al. Among authors: wald dn. Blood Adv. 2023 Dec 12;7(23):7185-7189. doi: 10.1182/bloodadvances.2022008094. Blood Adv. 2023. PMID: 37922427 Free PMC article. No abstract available.
Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function.
Wang W, Zimmerman G, Huang X, Yu S, Myers J, Wang Y, Moreton S, Nthale J, Awadallah A, Beck R, Xin W, Wald D, Huang AY, Zhou L. Wang W, et al. Among authors: wald d. Cancer Res. 2016 Mar 15;76(6):1641-52. doi: 10.1158/0008-5472.CAN-15-2092. Epub 2016 Jan 22. Cancer Res. 2016. PMID: 26801976 Free PMC article.
Aberrant GSK3β nuclear localization promotes AML growth and drug resistance.
Ignatz-Hoover JJ, Wang V, Mackowski NM, Roe AJ, Ghansah IK, Ueda M, Lazarus HM, de Lima M, Paietta E, Fernandez H, Cripe L, Tallman M, Wald DN. Ignatz-Hoover JJ, et al. Blood Adv. 2018 Nov 13;2(21):2890-2903. doi: 10.1182/bloodadvances.2018016006. Blood Adv. 2018. PMID: 30385433 Free PMC article.
221 results