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Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic.
Sacha JB, Kim IJ, Chen L, Ullah JH, Goodwin DA, Simmons HA, Schenkman DI, von Pelchrzim F, Gifford RJ, Nimityongskul FA, Newman LP, Wildeboer S, Lappin PB, Hammond D, Castrovinci P, Piaskowski SM, Reed JS, Beheler KA, Tharmanathan T, Zhang N, Muscat-King S, Rieger M, Fernandes C, Rumpel K, Gardner JP 2nd, Gebhard DH, Janies J, Shoieb A, Pierce BG, Trajkovic D, Rakasz E, Rong S, McCluskie M, Christy C, Merson JR, Jones RB, Nixon DF, Ostrowski MA, Loudon PT, Pruimboom-Brees IM, Sheppard NC. Sacha JB, et al. Among authors: zhang n. J Immunol. 2012 Aug 1;189(3):1467-79. doi: 10.4049/jimmunol.1200079. Epub 2012 Jun 27. J Immunol. 2012. PMID: 22745376 Free PMC article.
Anti-nicotine vaccines: Comparison of adjuvanted CRM197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates.
McCluskie MJ, Thorn J, Gervais DP, Stead DR, Zhang N, Benoit M, Cartier J, Kim IJ, Bhattacharya K, Finneman JI, Merson JR, Davis HL. McCluskie MJ, et al. Among authors: zhang n. Int Immunopharmacol. 2015 Dec;29(2):663-671. doi: 10.1016/j.intimp.2015.09.012. Epub 2015 Sep 26. Int Immunopharmacol. 2015. PMID: 26404190
The effect of preexisting anti-carrier immunity on subsequent responses to CRM197 or Qb-VLP conjugate vaccines.
McCluskie MJ, Evans DM, Zhang N, Benoit M, McElhiney SP, Unnithan M, DeMarco SC, Clay B, Huber C, Deora A, Thorn JM, Stead DR, Merson JR, Davis HL. McCluskie MJ, et al. Among authors: zhang n. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):184-96. doi: 10.3109/08923973.2016.1165246. Epub 2016 Apr 27. Immunopharmacol Immunotoxicol. 2016. PMID: 27121368
Molecular attributes of conjugate antigen influence function of antibodies induced by anti-nicotine vaccine in mice and non-human primates.
McCluskie MJ, Thorn J, Mehelic PR, Kolhe P, Bhattacharya K, Finneman JI, Stead DR, Piatchek MB, Zhang N, Chikh G, Cartier J, Evans DM, Merson JR, Davis HL. McCluskie MJ, et al. Among authors: zhang n. Int Immunopharmacol. 2015 Apr;25(2):518-27. doi: 10.1016/j.intimp.2015.02.030. Epub 2015 Feb 28. Int Immunopharmacol. 2015. PMID: 25737198
Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice.
Pryde DC, Jones LH, Gervais DP, Stead DR, Blakemore DC, Selby MD, Brown AD, Coe JW, Badland M, Beal DM, Glen R, Wharton Y, Miller GJ, White P, Zhang N, Benoit M, Robertson K, Merson JR, Davis HL, McCluskie MJ. Pryde DC, et al. Among authors: zhang n. PLoS One. 2013 Oct 1;8(10):e76557. doi: 10.1371/journal.pone.0076557. eCollection 2013. PLoS One. 2013. PMID: 24098532 Free PMC article.
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