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B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody.
Herbst R, Wang Y, Gallagher S, Mittereder N, Kuta E, Damschroder M, Woods R, Rowe DC, Cheng L, Cook K, Evans K, Sims GP, Pfarr DS, Bowen MA, Dall'Acqua W, Shlomchik M, Tedder TF, Kiener P, Jallal B, Wu H, Coyle AJ. Herbst R, et al. J Pharmacol Exp Ther. 2010 Oct;335(1):213-22. doi: 10.1124/jpet.110.168062. Epub 2010 Jul 6. J Pharmacol Exp Ther. 2010. PMID: 20605905
CD19 and CD32b differentially regulate human B cell responsiveness.
Karnell JL, Dimasi N, Karnell FG 3rd, Fleming R, Kuta E, Wilson M, Wu H, Gao C, Herbst R, Ettinger R. Karnell JL, et al. Among authors: herbst r. J Immunol. 2014 Feb 15;192(4):1480-90. doi: 10.4049/jimmunol.1301361. Epub 2014 Jan 17. J Immunol. 2014. PMID: 24442430 Free PMC article.
Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
Henault J, Riggs JM, Karnell JL, Liarski VM, Li J, Shirinian L, Xu L, Casey KA, Smith MA, Khatry DB, Izhak L, Clarke L, Herbst R, Ettinger R, Petri M, Clark MR, Mustelin T, Kolbeck R, Sanjuan MA. Henault J, et al. Among authors: herbst r. Nat Immunol. 2016 Feb;17(2):196-203. doi: 10.1038/ni.3326. Epub 2015 Dec 21. Nat Immunol. 2016. PMID: 26692173 Free PMC article.
A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response.
Xiao Z, Carrasco RA, Schifferli K, Kinneer K, Tammali R, Chen H, Rothstein R, Wetzel L, Yang C, Chowdhury P, Tsui P, Steiner P, Jallal B, Herbst R, Hollingsworth RE, Tice DA. Xiao Z, et al. Among authors: herbst r. Mol Cancer Ther. 2016 Apr;15(4):689-701. doi: 10.1158/1535-7163.MCT-15-0555. Epub 2016 Feb 15. Mol Cancer Ther. 2016. PMID: 26880266
Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy.
Varkey R, Du Q, Karnell JL, Xiao X, Casey KA, Woods R, Rosenthal K, Wilson S, Dall'Acqua WF, Wu H, Herbst R, Ettinger R, Damschroder M. Varkey R, et al. Among authors: herbst r. PLoS One. 2019 Jan 25;14(1):e0211236. doi: 10.1371/journal.pone.0211236. eCollection 2019. PLoS One. 2019. PMID: 30682117 Free PMC article.
920 results