McCormick F - Search Results

1

A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1.

Stowe IB, Mercado EL, Stowe TR, Bell EL, Oses-Prieto JA, Hernández H, Burlingame AL, McCormick F. Stowe IB, et al. Among authors: mccormick f. Genes Dev. 2012 Jul 1;26(13):1421-6. doi: 10.1101/gad.190876.112. Genes Dev. 2012. PMID: 22751498 Free PMC article.

2

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

Timmerman LA, Grego-Bessa J, Raya A, Bertrán E, Pérez-Pomares JM, Díez J, Aranda S, Palomo S, McCormick F, Izpisúa-Belmonte JC, de la Pompa JL. Timmerman LA, et al. Among authors: mccormick f. Genes Dev. 2004 Jan 1;18(1):99-115. doi: 10.1101/gad.276304. Epub 2003 Dec 30. Genes Dev. 2004. PMID: 14701881 Free PMC article.

3

A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity.

Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, Fried M, McCormick F. Rodriguez-Viciana P, et al. Among authors: mccormick f. Mol Cell. 2006 Apr 21;22(2):217-30. doi: 10.1016/j.molcel.2006.03.027. Mol Cell. 2006. PMID: 16630891 Free article.

4

Critical role for arginine methylation in adenovirus-infected cells.

Iacovides DC, O'Shea CC, Oses-Prieto J, Burlingame A, McCormick F. Iacovides DC, et al. Among authors: mccormick f. J Virol. 2007 Dec;81(23):13209-17. doi: 10.1128/JVI.01415-06. Epub 2007 Aug 8. J Virol. 2007. PMID: 17686851 Free PMC article.

5

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint.

Lee SH, Sterling H, Burlingame A, McCormick F. Lee SH, et al. Among authors: mccormick f. Genes Dev. 2008 Nov 1;22(21):2926-31. doi: 10.1101/gad.1677208. Genes Dev. 2008. PMID: 18981471 Free PMC article.

6

The RasGAP proteins Ira2 and neurofibromin are negatively regulated by Gpb1 in yeast and ETEA in humans.

Phan VT, Ding VW, Li F, Chalkley RJ, Burlingame A, McCormick F. Phan VT, et al. Among authors: mccormick f. Mol Cell Biol. 2010 May;30(9):2264-79. doi: 10.1128/MCB.01450-08. Epub 2010 Feb 16. Mol Cell Biol. 2010. PMID: 20160012 Free PMC article.

7

Therapeutic strategies for targeting ras proteins.

Gysin S, Salt M, Young A, McCormick F. Gysin S, et al. Among authors: mccormick f. Genes Cancer. 2011 Mar;2(3):359-72. doi: 10.1177/1947601911412376. Genes Cancer. 2011. PMID: 21779505 Free PMC article.

8

Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.

Sos ML, Levin RS, Gordan JD, Oses-Prieto JA, Webber JT, Salt M, Hann B, Burlingame AL, McCormick F, Bandyopadhyay S, Shokat KM. Sos ML, et al. Among authors: mccormick f. Cell Rep. 2014 Aug 21;8(4):1037-48. doi: 10.1016/j.celrep.2014.07.010. Epub 2014 Aug 7. Cell Rep. 2014. PMID: 25127139 Free PMC article.

9

The neurofibromin recruitment factor Spred1 binds to the GAP related domain without affecting Ras inactivation.

Dunzendorfer-Matt T, Mercado EL, Maly K, McCormick F, Scheffzek K. Dunzendorfer-Matt T, et al. Among authors: mccormick f. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7497-502. doi: 10.1073/pnas.1607298113. Epub 2016 Jun 16. Proc Natl Acad Sci U S A. 2016. PMID: 27313208 Free PMC article.

10

SHOC2-MRAS-PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis.

Young LC, Hartig N, Boned Del Río I, Sari S, Ringham-Terry B, Wainwright JR, Jones GG, McCormick F, Rodriguez-Viciana P. Young LC, et al. Among authors: mccormick f. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10576-E10585. doi: 10.1073/pnas.1720352115. Epub 2018 Oct 22. Proc Natl Acad Sci U S A. 2018. PMID: 30348783 Free PMC article.

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