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Anti-apoptotic action of (2S,3S,4R)-N"-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine (KR-31378) by suppression of the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and increased phosphorylation of casein kinase2/Akt/ cyclic AMP response element binding protein via maxi-K channel opening in neuronal cells.
Kim KY, Lee JH, Park JH, Yoo MA, Kwak YG, Kim SO, Yoo SE, Hong KW. Kim KY, et al. Among authors: kim so. Eur J Pharmacol. 2004 Aug 30;497(3):267-77. doi: 10.1016/j.ejphar.2004.06.058. Eur J Pharmacol. 2004. PMID: 15336944
Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors.
Ahn JH, Park WS, Jun MA, Shin MS, Kang SK, Kim KY, Rhee SD, Bae MA, Kim KR, Kim SG, Kim SY, Sohn SK, Kang NS, Lee JO, Lee DH, Cheon HG, Kim SS. Ahn JH, et al. Among authors: kim ss, kim sg, kim sy, kim kr, kim ky. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6525-9. doi: 10.1016/j.bmcl.2008.10.076. Epub 2008 Oct 21. Bioorg Med Chem Lett. 2008. PMID: 18996694
2,054 results