Lau AW - Search Results

1

Acetylation-dependent regulation of Skp2 function.

Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, Haigis MC, Pandolfi PP, Wei W. Inuzuka H, et al. Among authors: lau aw. Cell. 2012 Jul 6;150(1):179-93. doi: 10.1016/j.cell.2012.05.038. Cell. 2012. PMID: 22770219 Free PMC article.

2

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.

Min SH, Lau AW, Lee TH, Inuzuka H, Wei S, Huang P, Shaik S, Lee DY, Finn G, Balastik M, Chen CH, Luo M, Tron AE, Decaprio JA, Zhou XZ, Wei W, Lu KP. Min SH, et al. Among authors: lau aw. Mol Cell. 2012 Jun 29;46(6):771-83. doi: 10.1016/j.molcel.2012.04.012. Epub 2012 May 17. Mol Cell. 2012. PMID: 22608923 Free PMC article.

3

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. Fukushima H, et al. Among authors: lau aw. Cell Rep. 2012 May 31;1(5):434-43. doi: 10.1016/j.celrep.2012.04.002. Cell Rep. 2012. PMID: 22708077 Free PMC article.

4

Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.

Lau AW, Inuzuka H, Fukushima H, Wan L, Liu P, Gao D, Sun Y, Wei W. Lau AW, et al. Cell Res. 2013 Jul;23(7):947-61. doi: 10.1038/cr.2013.67. Epub 2013 May 14. Cell Res. 2013. PMID: 23670162 Free PMC article.

5

SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression.

Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W. Fukushima H, et al. Among authors: lau aw. Cell Rep. 2013 Aug 29;4(4):803-16. doi: 10.1016/j.celrep.2013.07.031. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972993 Free PMC article.

6

SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer.

Gasser JA, Inuzuka H, Lau AW, Wei W, Beroukhim R, Toker A. Gasser JA, et al. Among authors: lau aw. Mol Cell. 2014 Nov 20;56(4):595-607. doi: 10.1016/j.molcel.2014.09.023. Epub 2014 Oct 30. Mol Cell. 2014. PMID: 25458846 Free PMC article.

7

Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.

Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W. Gao D, et al. Mol Cell. 2010 Sep 10;39(5):797-808. doi: 10.1016/j.molcel.2010.08.016. Mol Cell. 2010. PMID: 20832730 Free PMC article.

8

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. Inuzuka H, et al. Among authors: lau aw. Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732. Nature. 2011. PMID: 21368833 Free PMC article.

9

Mcl-1 ubiquitination and destruction.

Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Inuzuka H, et al. Among authors: lau aw. Oncotarget. 2011 Mar;2(3):239-44. doi: 10.18632/oncotarget.242. Oncotarget. 2011. PMID: 21608150 Free PMC article. Review.

10

The two faces of FBW7 in cancer drug resistance.

Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W. Wang Z, et al. Among authors: lau aw. Bioessays. 2011 Nov;33(11):851-9. doi: 10.1002/bies.201100101. Epub 2011 Aug 30. Bioessays. 2011. PMID: 22006825 Free PMC article. Review.

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