Kong Y - Search Results

1

Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells.

Yenugonda VM, Kong Y, Deb TB, Yang Y, Riggins RB, Brown ML. Yenugonda VM, et al. Among authors: kong y. Cancer Biol Ther. 2012 Aug;13(10):925-34. doi: 10.4161/cbt.20845. Epub 2012 Aug 1. Cancer Biol Ther. 2012. PMID: 22785207 Free PMC article.

2

Structure-based discovery of a boronic acid bioisostere of combretastatin A-4.

Kong Y, Grembecka J, Edler MC, Hamel E, Mooberry SL, Sabat M, Rieger J, Brown ML. Kong Y, et al. Chem Biol. 2005 Sep;12(9):1007-14. doi: 10.1016/j.chembiol.2005.06.016. Chem Biol. 2005. PMID: 16183025

3

Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta.

Gorczynski MJ, Grembecka J, Zhou Y, Kong Y, Roudaia L, Douvas MG, Newman M, Bielnicka I, Baber G, Corpora T, Shi J, Sridharan M, Lilien R, Donald BR, Speck NA, Brown ML, Bushweller JH. Gorczynski MJ, et al. Among authors: kong y. Chem Biol. 2007 Oct;14(10):1186-97. doi: 10.1016/j.chembiol.2007.09.006. Chem Biol. 2007. PMID: 17961830

4

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma.

Erkizan HV, Kong Y, Merchant M, Schlottmann S, Barber-Rotenberg JS, Yuan L, Abaan OD, Chou TH, Dakshanamurthy S, Brown ML, Uren A, Toretsky JA. Erkizan HV, et al. Among authors: kong y. Nat Med. 2009 Jul;15(7):750-6. doi: 10.1038/nm.1983. Epub 2009 Jul 5. Nat Med. 2009. PMID: 19584866 Free PMC article.

5

A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent.

Kong Y, Wang K, Edler MC, Hamel E, Mooberry SL, Paige MA, Brown ML. Kong Y, et al. Bioorg Med Chem. 2010 Jan 15;18(2):971-7. doi: 10.1016/j.bmc.2009.11.003. Epub 2009 Nov 10. Bioorg Med Chem. 2010. PMID: 20006519 Free PMC article.

6

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.

Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM. Awad O, et al. Among authors: kong y. PLoS One. 2010 Nov 11;5(11):e13943. doi: 10.1371/journal.pone.0013943. PLoS One. 2010. PMID: 21085683 Free PMC article.

7

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

Rahim S, Beauchamp EM, Kong Y, Brown ML, Toretsky JA, Üren A. Rahim S, et al. Among authors: kong y. PLoS One. 2011 Apr 29;6(4):e19343. doi: 10.1371/journal.pone.0019343. PLoS One. 2011. PMID: 21559405 Free PMC article.

8

Histone deacetylase cytoplasmic trapping by a novel fluorescent HDAC inhibitor.

Kong Y, Jung M, Wang K, Grindrod S, Velena A, Lee SA, Dakshanamurthy S, Yang Y, Miessau M, Zheng C, Dritschilo A, Brown ML. Kong Y, et al. Mol Cancer Ther. 2011 Sep;10(9):1591-9. doi: 10.1158/1535-7163.MCT-10-0779. Epub 2011 Jun 22. Mol Cancer Ther. 2011. PMID: 21697394 Free PMC article.

9

Asymmetric synthesis and evaluation of a hydroxyphenylamide voltage-gated sodium channel blocker in human prostate cancer xenografts.

Davis GC, Kong Y, Paige M, Li Z, Merrick EC, Hansen T, Suy S, Wang K, Dakshanamurthy S, Cordova A, McManus OB, Williams BS, Chruszcz M, Minor W, Patel MK, Brown ML. Davis GC, et al. Among authors: kong y. Bioorg Med Chem. 2012 Mar 15;20(6):2180-8. doi: 10.1016/j.bmc.2011.08.061. Epub 2011 Sep 1. Bioorg Med Chem. 2012. PMID: 22364743 Free PMC article.

10

Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.

Barber-Rotenberg JS, Selvanathan SP, Kong Y, Erkizan HV, Snyder TM, Hong SP, Kobs CL, South NL, Summer S, Monroe PJ, Chruszcz M, Dobrev V, Tosso PN, Scher LJ, Minor W, Brown ML, Metallo SJ, Üren A, Toretsky JA. Barber-Rotenberg JS, et al. Among authors: kong y. Oncotarget. 2012 Feb;3(2):172-82. doi: 10.18632/oncotarget.454. Oncotarget. 2012. PMID: 22383402 Free PMC article.

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