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Page 1
Atherosclerosis in Octodon degus (degu) as a model for human disease.
Homan R, Hanselman JC, Bak-Mueller S, Washburn M, Lester P, Jensen HE, Pinkosky SL, Castle C, Taylor B. Homan R, et al. Among authors: hanselman jc. Atherosclerosis. 2010 Sep;212(1):48-54. doi: 10.1016/j.atherosclerosis.2010.06.004. Epub 2010 Jun 11. Atherosclerosis. 2010. PMID: 20630529
AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism.
Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS. Pinkosky SL, et al. Among authors: hanselman jc. J Lipid Res. 2013 Jan;54(1):134-51. doi: 10.1194/jlr.M030528. Epub 2012 Nov 1. J Lipid Res. 2013. PMID: 23118444 Free PMC article.
Efficacy and safety of ETC-1002, a novel investigational low-density lipoprotein-cholesterol-lowering therapy for the treatment of patients with hypercholesterolemia and type 2 diabetes mellitus.
Gutierrez MJ, Rosenberg NL, Macdougall DE, Hanselman JC, Margulies JR, Strange P, Milad MA, McBride SJ, Newton RS. Gutierrez MJ, et al. Among authors: hanselman jc. Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):676-83. doi: 10.1161/ATVBAHA.113.302677. Epub 2014 Jan 2. Arterioscler Thromb Vasc Biol. 2014. PMID: 24385236 Clinical Trial.
Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance.
Thompson PD, MacDougall DE, Newton RS, Margulies JR, Hanselman JC, Orloff DG, McKenney JM, Ballantyne CM. Thompson PD, et al. Among authors: hanselman jc. J Clin Lipidol. 2016 May-Jun;10(3):556-67. doi: 10.1016/j.jacl.2015.12.025. Epub 2016 Jan 6. J Clin Lipidol. 2016. PMID: 27206943 Free article. Clinical Trial.
Complementary low-density lipoprotein-cholesterol lowering and pharmacokinetics of adding bempedoic acid (ETC-1002) to high-dose atorvastatin background therapy in hypercholesterolemic patients: A randomized placebo-controlled trial.
Lalwani ND, Hanselman JC, MacDougall DE, Sterling LR, Cramer CT. Lalwani ND, et al. Among authors: hanselman jc. J Clin Lipidol. 2019 Jul-Aug;13(4):568-579. doi: 10.1016/j.jacl.2019.05.003. Epub 2019 May 13. J Clin Lipidol. 2019. PMID: 31202641 Clinical Trial.
30 results