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AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism.
Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS. Pinkosky SL, et al. Among authors: srivastava ra. J Lipid Res. 2013 Jan;54(1):134-51. doi: 10.1194/jlr.M030528. Epub 2012 Nov 1. J Lipid Res. 2013. PMID: 23118444 Free PMC article.
Corrigendum to "Discovery of analogues of non-β oxidizable long-chain dicarboxylic fatty acids as dual inhibitors of fatty acids and cholesterol synthesis: Efficacy of lead compound in hyperlipidemic hamsters reveals novel mechanism" [Nutr Metabol Cardiovasc Dis 31 (2021) 2490-2703].
Srivastava RAK, Hurley TR, Oniciu D, Adeli K, Newton RS. Srivastava RAK, et al. Nutr Metab Cardiovasc Dis. 2022 Jan;32(1):290-293. doi: 10.1016/j.numecd.2021.10.002. Epub 2021 Dec 8. Nutr Metab Cardiovasc Dis. 2022. PMID: 34893416 No abstract available.
72 results