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Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
Van Rompay KK, Trott KA, Jayashankar K, Geng Y, LaBranche CC, Johnson JA, Landucci G, Lipscomb J, Tarara RP, Canfield DR, Heneine W, Forthal DN, Montefiori D, Abel K. Van Rompay KK, et al. Among authors: canfield dr. Retrovirology. 2012 Jul 17;9:57. doi: 10.1186/1742-4690-9-57. Retrovirology. 2012. PMID: 22805180 Free PMC article.
The clinical benefits of tenofovir for simian immunodeficiency virus-infected macaques are larger than predicted by its effects on standard viral and immunologic parameters.
Van Rompay KK, Singh RP, Brignolo LL, Lawson JR, Schmidt KA, Pahar B, Canfield DR, Tarara RP, Sodora DL, Bischofberger N, Marthas ML. Van Rompay KK, et al. Among authors: canfield dr. J Acquir Immune Defic Syndr. 2004 Aug 1;36(4):900-14. doi: 10.1097/00126334-200408010-00003. J Acquir Immune Defic Syndr. 2004. PMID: 15220696
Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251.
Van Rompay KK, Greenier JL, Cole KS, Earl P, Moss B, Steckbeck JD, Pahar B, Rourke T, Montelaro RC, Canfield DR, Tarara RP, Miller C, McChesney MB, Marthas ML. Van Rompay KK, et al. Among authors: canfield dr. J Virol. 2003 Jan;77(1):179-90. doi: 10.1128/jvi.77.1.179-190.2003. J Virol. 2003. PMID: 12477823 Free PMC article.
Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques.
Van Rompay KK, Brignolo LL, Meyer DJ, Jerome C, Tarara R, Spinner A, Hamilton M, Hirst LL, Bennett DR, Canfield DR, Dearman TG, Von Morgenland W, Allen PC, Valverde C, Castillo AB, Martin RB, Samii VF, Bendele R, Desjardins J, Marthas ML, Pedersen NC, Bischofberger N. Van Rompay KK, et al. Among authors: canfield dr. Antimicrob Agents Chemother. 2004 May;48(5):1469-87. doi: 10.1128/AAC.48.5.1469-1487.2004. Antimicrob Agents Chemother. 2004. PMID: 15105094 Free PMC article.
9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques.
Van Rompay KK, Cherrington JM, Marthas ML, Berardi CJ, Mulato AS, Spinner A, Tarara RP, Canfield DR, Telm S, Bischofberger N, Pedersen NC. Van Rompay KK, et al. Among authors: canfield dr. Antimicrob Agents Chemother. 1996 Nov;40(11):2586-91. doi: 10.1128/AAC.40.11.2586. Antimicrob Agents Chemother. 1996. PMID: 8913470 Free PMC article.
67 results