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A whole-cell computational model predicts phenotype from genotype.
Karr JR, Sanghvi JC, Macklin DN, Gutschow MV, Jacobs JM, Bolival B Jr, Assad-Garcia N, Glass JI, Covert MW. Karr JR, et al. Among authors: macklin dn. Cell. 2012 Jul 20;150(2):389-401. doi: 10.1016/j.cell.2012.05.044. Cell. 2012. PMID: 22817898 Free PMC article.
The future of whole-cell modeling.
Macklin DN, Ruggero NA, Covert MW. Macklin DN, et al. Curr Opin Biotechnol. 2014 Aug;28:111-5. doi: 10.1016/j.copbio.2014.01.012. Epub 2014 Feb 17. Curr Opin Biotechnol. 2014. PMID: 24556244 Free PMC article. Review.
Simultaneous cross-evaluation of heterogeneous E. coli datasets via mechanistic simulation.
Macklin DN, Ahn-Horst TA, Choi H, Ruggero NA, Carrera J, Mason JC, Sun G, Agmon E, DeFelice MM, Maayan I, Lane K, Spangler RK, Gillies TE, Paull ML, Akhter S, Bray SR, Weaver DS, Keseler IM, Karp PD, Morrison JH, Covert MW. Macklin DN, et al. Science. 2020 Jul 24;369(6502):eaav3751. doi: 10.1126/science.aav3751. Science. 2020. PMID: 32703847 Free PMC article.