Prevo R - Search Results

1

The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.

Prevo R, Fokas E, Reaper PM, Charlton PA, Pollard JR, McKenna WG, Muschel RJ, Brunner TB. Prevo R, et al. Cancer Biol Ther. 2012 Sep;13(11):1072-81. doi: 10.4161/cbt.21093. Epub 2012 Jul 24. Cancer Biol Ther. 2012. PMID: 22825331 Free PMC article.

2

Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity.

Prevo R, Deutsch E, Sampson O, Diplexcito J, Cengel K, Harper J, O'Neill P, McKenna WG, Patel S, Bernhard EJ. Prevo R, et al. Cancer Res. 2008 Jul 15;68(14):5915-23. doi: 10.1158/0008-5472.CAN-08-0757. Cancer Res. 2008. PMID: 18632646

3

A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.

Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. Higgins GS, et al. Among authors: prevo r. Cancer Res. 2010 Apr 1;70(7):2984-93. doi: 10.1158/0008-5472.CAN-09-4040. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233878 Free PMC article.

4

Overexpression of POLQ confers a poor prognosis in early breast cancer patients.

Higgins GS, Harris AL, Prevo R, Helleday T, McKenna WG, Buffa FM. Higgins GS, et al. Among authors: prevo r. Oncotarget. 2010 Jul;1(3):175-84. doi: 10.18632/oncotarget.124. Oncotarget. 2010. PMID: 20700469 Free PMC article.

5

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.

Fokas E, Yoshimura M, Prevo R, Higgins G, Hackl W, Maira SM, Bernhard EJ, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: prevo r. Radiat Oncol. 2012 Mar 27;7:48. doi: 10.1186/1748-717X-7-48. Radiat Oncol. 2012. PMID: 22452803 Free PMC article.

6

Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.

Nicolay NH, Carter R, Hatch SB, Schultz N, Prevo R, McKenna WG, Helleday T, Sharma RA. Nicolay NH, et al. Among authors: prevo r. Carcinogenesis. 2012 Nov;33(11):2026-34. doi: 10.1093/carcin/bgs239. Epub 2012 Jul 20. Carcinogenesis. 2012. PMID: 22822095 Free PMC article.

7

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

Fokas E, Prevo R, Pollard JR, Reaper PM, Charlton PA, Cornelissen B, Vallis KA, Hammond EM, Olcina MM, Gillies McKenna W, Muschel RJ, Brunner TB. Fokas E, et al. Among authors: prevo r. Cell Death Dis. 2012 Dec 6;3(12):e441. doi: 10.1038/cddis.2012.181. Cell Death Dis. 2012. PMID: 23222511 Free PMC article.

8

Targeting ATR in DNA damage response and cancer therapeutics.

Fokas E, Prevo R, Hammond EM, Brunner TB, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: prevo r. Cancer Treat Rev. 2014 Feb;40(1):109-17. doi: 10.1016/j.ctrv.2013.03.002. Epub 2013 Apr 11. Cancer Treat Rev. 2014. PMID: 23583268 Review.

9

Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen.

Tiwana GS, Prevo R, Buffa FM, Yu S, Ebner DV, Howarth A, Folkes LK, Budwal B, Chu KY, Durrant L, Muschel RJ, McKenna WG, Higgins GS. Tiwana GS, et al. Among authors: prevo r. Oncotarget. 2015 Mar 20;6(8):5978-89. doi: 10.18632/oncotarget.3468. Oncotarget. 2015. PMID: 25788274 Free PMC article.

10

Depletion of signal recognition particle 72kDa increases radiosensitivity.

Prevo R, Tiwana GS, Maughan TS, Buffa FM, McKenna WG, Higgins GS. Prevo R, et al. Cancer Biol Ther. 2017 Jun 3;18(6):425-432. doi: 10.1080/15384047.2017.1323587. Epub 2017 May 11. Cancer Biol Ther. 2017. PMID: 28494188 Free PMC article.

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