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Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels.
Peyronnet R, Sharif-Naeini R, Folgering JH, Arhatte M, Jodar M, El Boustany C, Gallian C, Tauc M, Duranton C, Rubera I, Lesage F, Pei Y, Peters DJ, Somlo S, Sachs F, Patel A, Honoré E, Duprat F. Peyronnet R, et al. Among authors: el boustany c. Cell Rep. 2012 Mar 29;1(3):241-50. doi: 10.1016/j.celrep.2012.01.006. Epub 2012 Mar 8. Cell Rep. 2012. PMID: 22832196 Free PMC article.
TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.
Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A. Arhatte M, et al. Among authors: el boustany c. Nat Commun. 2019 May 2;10(1):2024. doi: 10.1038/s41467-019-10045-y. Nat Commun. 2019. PMID: 31048699 Free PMC article.
Sodium Butyrate (NaB) and Sodium Propionate (NaP) Reduce Cyclin A2 Expression, Inducing Cell Cycle Arrest and Proliferation Inhibition of Different Breast Cancer Subtypes, Leading to Apoptosis.
Ibrahim JN, El-Hakim S, Semaan J, Ghosn S, El Ayoubi H, Elnar AA, Tohme N, El Boustany C. Ibrahim JN, et al. Among authors: el boustany c. Biomedicines. 2024 Aug 6;12(8):1779. doi: 10.3390/biomedicines12081779. Biomedicines. 2024. PMID: 39200243 Free PMC article.