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Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression.
Sisirak V, Faget J, Gobert M, Goutagny N, Vey N, Treilleux I, Renaudineau S, Poyet G, Labidi-Galy SI, Goddard-Leon S, Durand I, Le Mercier I, Bajard A, Bachelot T, Puisieux A, Puisieux I, Blay JY, Ménétrier-Caux C, Caux C, Bendriss-Vermare N. Sisirak V, et al. Among authors: le mercier i. Cancer Res. 2012 Oct 15;72(20):5188-97. doi: 10.1158/0008-5472.CAN-11-3468. Epub 2012 Jul 25. Cancer Res. 2012. PMID: 22836755
Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.
Deng J, Li J, Sarde A, Lines JL, Lee YC, Qian DC, Pechenick DA, Manivanh R, Le Mercier I, Lowrey CH, Varn FS, Cheng C, Leib DA, Noelle RJ, Mabaera R. Deng J, et al. Among authors: le mercier i. Cancer Immunol Res. 2019 Jul;7(7):1079-1090. doi: 10.1158/2326-6066.CIR-18-0507. Epub 2019 May 14. Cancer Immunol Res. 2019. PMID: 31088847 Free PMC article.
Immunoregulatory functions of VISTA.
Nowak EC, Lines JL, Varn FS, Deng J, Sarde A, Mabaera R, Kuta A, Le Mercier I, Cheng C, Noelle RJ. Nowak EC, et al. Among authors: le mercier i. Immunol Rev. 2017 Mar;276(1):66-79. doi: 10.1111/imr.12525. Immunol Rev. 2017. PMID: 28258694 Free PMC article. Review.
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance.
ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, Hogquist KA, Jameson SC, Mueller D, Rothstein J, Blazar BR, Cheng C, Noelle RJ. ElTanbouly MA, et al. Among authors: le mercier i. Science. 2020 Jan 17;367(6475):eaay0524. doi: 10.1126/science.aay0524. Science. 2020. PMID: 31949051 Free PMC article.
Tryptophan hydroxylase-1 regulates immune tolerance and inflammation.
Nowak EC, de Vries VC, Wasiuk A, Ahonen C, Bennett KA, Le Mercier I, Ha DG, Noelle RJ. Nowak EC, et al. Among authors: le mercier i. J Exp Med. 2012 Oct 22;209(11):2127-35. doi: 10.1084/jem.20120408. Epub 2012 Sep 24. J Exp Med. 2012. PMID: 23008335 Free PMC article.
13 results