Ieiri I - Search Results

1

Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing.

Ieiri I, Fukae M, Maeda K, Ando Y, Kimura M, Hirota T, Nakamura T, Iwasaki K, Matsuki S, Matsuguma K, Kanda E, Deguchi M, Irie S, Sugiyama Y. Ieiri I, et al. Int J Clin Pharmacol Ther. 2012 Oct;50(10):689-700. doi: 10.5414/CP201763. Int J Clin Pharmacol Ther. 2012. PMID: 22853867

2

Pharmacokinetics of omeprazole (a substrate of CYP2C19) and comparison with two mutant alleles, C gamma P2C19m1 in exon 5 and C gamma P2C19m2 in exon 4, in Japanese subjects.

Ieiri I, Kubota T, Urae A, Kimura M, Wada Y, Mamiya K, Yoshioka S, Irie S, Amamoto T, Nakamura K, Nakano S, Higuchi S. Ieiri I, et al. Clin Pharmacol Ther. 1996 Jun;59(6):647-53. doi: 10.1016/S0009-9236(96)90004-1. Clin Pharmacol Ther. 1996. PMID: 8681489

3

Stereoselective 4'-hydroxylation of phenytoin: relationship to (S)-mephenytoin polymorphism in Japanese.

Ieiri I, Mamiya K, Urae A, Wada Y, Kimura M, Irie S, Amamoto T, Kubota T, Yoshioka S, Nakamura K, Nakano S, Tashiro N, Higuchi S. Ieiri I, et al. Br J Clin Pharmacol. 1997 Apr;43(4):441-5. doi: 10.1046/j.1365-2125.1997.00572.x. Br J Clin Pharmacol. 1997. PMID: 9146858 Free PMC article. Clinical Trial.

4

Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population.

Kimura M, Ieiri I, Mamiya K, Urae A, Higuchi S. Kimura M, et al. Among authors: ieiri i. Ther Drug Monit. 1998 Jun;20(3):243-7. doi: 10.1097/00007691-199806000-00001. Ther Drug Monit. 1998. PMID: 9631918

5

Reliability of the omeprazole hydroxylation index for CYP2C19 phenotyping: possible effect of age, liver disease and length of therapy.

Kimura M, Ieiri I, Wada Y, Mamiya K, Urae A, Iimori E, Sakai T, Otsubo K, Higuchi S. Kimura M, et al. Among authors: ieiri i. Br J Clin Pharmacol. 1999 Jan;47(1):115-9. doi: 10.1046/j.1365-2125.1999.00858.x. Br J Clin Pharmacol. 1999. PMID: 10073749 Free PMC article. Clinical Trial.

6

CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: analysis by population pharmacokinetics.

Mamiya K, Hadama A, Yukawa E, Ieiri I, Otsubo K, Ninomiya H, Tashiro N, Higuchi S. Mamiya K, et al. Among authors: ieiri i. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):821-5. doi: 10.1007/s002280050703. Eur J Clin Pharmacol. 2000. PMID: 10805060 Clinical Trial.

7

Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9*3 allele.

Shimamoto J, Ieiri I, Urae A, Kimura M, Irie S, Kubota T, Chiba K, Ishizaki T, Otsubo K, Higuchi S. Shimamoto J, et al. Among authors: ieiri i. Eur J Clin Pharmacol. 2000 Apr;56(1):65-8. doi: 10.1007/s002280050722. Eur J Clin Pharmacol. 2000. PMID: 10853880

8

P-hydroxylation of phenobarbital: relationship to (S)-mephenytoin hydroxylation (CYP2C19) polymorphism.

Hadama A, Ieiri I, Morita T, Kimura M, Urae A, Irie S, Kaneda T, Mamiya K, Tashiro N, Higuchi S, Otsubo K. Hadama A, et al. Among authors: ieiri i. Ther Drug Monit. 2001 Apr;23(2):115-8. doi: 10.1097/00007691-200104000-00004. Ther Drug Monit. 2001. PMID: 11294510 Clinical Trial.

9

Genetic polymorphisms and functional characterization of the 5'-flanking region of the human CYP2C9 gene: in vitro and in vivo studies.

Shintani M, Ieiri I, Inoue K, Mamiya K, Ninomiya H, Tashiro N, Higuchi S, Otsubo K. Shintani M, et al. Among authors: ieiri i. Clin Pharmacol Ther. 2001 Aug;70(2):175-82. doi: 10.1067/mcp.2001.117367. Clin Pharmacol Ther. 2001. PMID: 11503012

10

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

Kurata Y, Ieiri I, Kimura M, Morita T, Irie S, Urae A, Ohdo S, Ohtani H, Sawada Y, Higuchi S, Otsubo K. Kurata Y, et al. Among authors: ieiri i. Clin Pharmacol Ther. 2002 Aug;72(2):209-19. doi: 10.1067/mcp.2002.126177. Clin Pharmacol Ther. 2002. PMID: 12189368

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