Manoharan M - Search Results

1

Intravesical delivery of small activating RNA formulated into lipid nanoparticles inhibits orthotopic bladder tumor growth.

Kang MR, Yang G, Place RF, Charisse K, Epstein-Barash H, Manoharan M, Li LC. Kang MR, et al. Among authors: manoharan m. Cancer Res. 2012 Oct 1;72(19):5069-79. doi: 10.1158/0008-5472.CAN-12-1871. Epub 2012 Aug 6. Cancer Res. 2012. PMID: 22869584

2

Direct CNS delivery of siRNA mediates robust silencing in oligodendrocytes.

Querbes W, Ge P, Zhang W, Fan Y, Costigan J, Charisse K, Maier M, Nechev L, Manoharan M, Kotelianski V, Sah DW. Querbes W, et al. Among authors: manoharan m. Oligonucleotides. 2009 Mar;19(1):23-29. doi: 10.1089/oli.2008.0165. Oligonucleotides. 2009. PMID: 19093781

3

Reversed-phase high-performance liquid chromatography method for simultaneous analysis of two liposome-formulated short interfering RNA duplexes.

Murugaiah V, Zedalis W, Lavine G, Charisse K, Manoharan M. Murugaiah V, et al. Among authors: manoharan m. Anal Biochem. 2010 Jun 1;401(1):61-7. doi: 10.1016/j.ab.2010.02.012. Epub 2010 Feb 13. Anal Biochem. 2010. PMID: 20156415

4

Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters.

Watts JK, Yu D, Charisse K, Montaillier C, Potier P, Manoharan M, Corey DR. Watts JK, et al. Among authors: manoharan m. Nucleic Acids Res. 2010 Aug;38(15):5242-59. doi: 10.1093/nar/gkq258. Epub 2010 Apr 19. Nucleic Acids Res. 2010. PMID: 20403811 Free PMC article.

5

Modulation of thermal stability can enhance the potency of siRNA.

Addepalli H, Meena, Peng CG, Wang G, Fan Y, Charisse K, Jayaprakash KN, Rajeev KG, Pandey RK, Lavine G, Zhang L, Jahn-Hofmann K, Hadwiger P, Manoharan M, Maier MA. Addepalli H, et al. Among authors: manoharan m. Nucleic Acids Res. 2010 Nov;38(20):7320-31. doi: 10.1093/nar/gkq568. Epub 2010 Jul 7. Nucleic Acids Res. 2010. PMID: 20610434 Free PMC article.

6

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.

Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG. Lee H, et al. Among authors: manoharan m. Nat Nanotechnol. 2012 Jun 3;7(6):389-93. doi: 10.1038/nnano.2012.73. Nat Nanotechnol. 2012. PMID: 22659608 Free PMC article.

7

An orthotopic bladder tumor model and the evaluation of intravesical saRNA treatment.

Kang MR, Yang G, Charisse K, Epstein-Barash H, Manoharan M, Li LC. Kang MR, et al. Among authors: manoharan m. J Vis Exp. 2012 Jul 28;(65):4207. doi: 10.3791/4207. J Vis Exp. 2012. PMID: 22872227 Free PMC article.

8

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data.

Patra A, Paolillo M, Charisse K, Manoharan M, Rozners E, Egli M. Patra A, et al. Among authors: manoharan m. Angew Chem Int Ed Engl. 2012 Nov 19;51(47):11863-6. doi: 10.1002/anie.201204946. Epub 2012 Oct 10. Angew Chem Int Ed Engl. 2012. PMID: 23055396 Free PMC article. No abstract available.

9

Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression.

Place RF, Wang J, Noonan EJ, Meyers R, Manoharan M, Charisse K, Duncan R, Huang V, Wang X, Li LC. Place RF, et al. Among authors: manoharan m. Mol Ther Nucleic Acids. 2012 Mar 27;1(3):e15. doi: 10.1038/mtna.2012.5. Mol Ther Nucleic Acids. 2012. PMID: 23343884 Free PMC article.

10

Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics.

Maier MA, Jayaraman M, Matsuda S, Liu J, Barros S, Querbes W, Tam YK, Ansell SM, Kumar V, Qin J, Zhang X, Wang Q, Panesar S, Hutabarat R, Carioto M, Hettinger J, Kandasamy P, Butler D, Rajeev KG, Pang B, Charisse K, Fitzgerald K, Mui BL, Du X, Cullis P, Madden TD, Hope MJ, Manoharan M, Akinc A. Maier MA, et al. Among authors: manoharan m. Mol Ther. 2013 Aug;21(8):1570-8. doi: 10.1038/mt.2013.124. Epub 2013 Jun 25. Mol Ther. 2013. PMID: 23799535 Free PMC article.

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